dc.creator | Martín-Reina, José | es |
dc.creator | Casanova, Alfredo G. | es |
dc.creator | Dahiri, Bouchra | es |
dc.creator | Fernández, Isaías | es |
dc.creator | Fernández Palacín, Ana | es |
dc.creator | Bautista Palomas, Juan Dionisio | es |
dc.creator | Morales, Ana I. | es |
dc.creator | Moreno Navarro, Isabel María | es |
dc.date.accessioned | 2022-11-03T16:24:34Z | |
dc.date.available | 2022-11-03T16:24:34Z | |
dc.date.issued | 2021-05-31 | |
dc.identifier.citation | Martín-Reina, J., Casanova, A.G., Dahiri, B., Fernández, I., Fernández Palacín, A., Bautista Palomas, J.D.,...,Moreno Navarro, I.M. (2021). Adverse health effects in women farmers indirectly exposed to pesticides. International Journal of Environmental Research and Public Health, 18 (11), 5909. https://doi.org/10.3390/ijerph18115909. | |
dc.identifier.issn | 1660-4601 | es |
dc.identifier.issn | 1661-7827 (electrónico) | es |
dc.identifier.uri | https://hdl.handle.net/11441/138680 | |
dc.description.abstract | Farmers are among the most vulnerable populations because of the exposure to low levels
of pesticides. Acetylcholinesterase and butyrylcholinesterase activities are considered as biomarkers
of pesticides poisoning. However, biomarkers of oxidative stress are also playing an important role
in toxicity of these contaminants. Further, increased activities of gamma-glutamyltransferase, alanine
aminotransferase, urea and creatinine have been linked with hepatic and nephrotoxic cell damage,
respectively. The aim of this study was to ascertain if the indirect exposure to pesticides leads to
some biochemical parameter changes. Thus, cholinesterase activities, oxidative stress status (lipid
and protein oxidation), hepatic function (AST and ALT levels), hormonal function (TSH, T4, FSH,
LH and AMH), renal function (serum creatinine and urea), as well as possible subclinical kidney
damage (urinary proteins and biomarkers of early kidney damage) were evaluated in farmer women
who collect fruits and vegetables comparing with a group of women non-occupational exposed to
pesticides but living in the same rural environment. Samples were taken periodically along one year
to relate the observed effects to a chronic exposure. Our main results showed for the first time a
subclinical kidney damage in a rural setting with indirect chronic exposure to pesticides. | es |
dc.format | application/pdf | es |
dc.format.extent | 17 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | International Journal of Environmental Research and Public Health, 18 (11), 5909. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Cholinesterase | es |
dc.subject | Oxidative stress | es |
dc.subject | Early kidney damage | es |
dc.subject | Pesticides | es |
dc.subject | Women farmers | es |
dc.title | Adverse health effects in women farmers indirectly exposed to pesticides | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina Preventiva y Salud Pública | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Nutrición y Bromatología, Toxicología y Medicina Legal | es |
dc.relation.publisherversion | https://www.mdpi.com/1660-4601/18/11/5909 | es |
dc.identifier.doi | 10.3390/ijerph18115909 | es |
dc.journaltitle | International Journal of Environmental Research and Public Health | es |
dc.publication.volumen | 18 | es |
dc.publication.issue | 11 | es |
dc.publication.initialPage | 5909 | es |