dc.creator | Marhuenda Muñoz, María | es |
dc.creator | de Alvarenga, José Fernando Rinaldi | es |
dc.creator | Hernáez, Álvaro | es |
dc.creator | Tresserra-Rimbau, Anna | es |
dc.creator | Martínez-González, Miguel Ángel | es |
dc.creator | Salas-Salvadó, Jordi | es |
dc.creator | Santos Lozano, José Manuel | es |
dc.creator | Lamuela-Raventós, Rosa M. | es |
dc.date.accessioned | 2022-10-11T15:43:23Z | |
dc.date.available | 2022-10-11T15:43:23Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Marhuenda-Muñoz, M., de Alvarenga, J.F.R., Hernáez, Á., Tresserra-Rimbau, A., Martínez-González, M.Á., Salas-Salvadó, J.,...,Lamuela-Raventós, R.M. (2021). High fruit and vegetable consumption and moderate fat intake are associated with higher carotenoid concentration in human plasma. Antioxidants, 10 (3). https://doi.org/10.3390/antiox10030473. | |
dc.identifier.issn | 2076-3921 | es |
dc.identifier.uri | https://hdl.handle.net/11441/137828 | |
dc.description.abstract | Carotenoids are pigments contained mainly in fruit and vegetables (F&V) that have bene ficial effects on cardiometabolic health. Due to their lipophilic nature, co-ingestion of fat appears to
increase their bioavailability via facilitating transfer to the aqueous micellar phase during diges tion. However, the extent to which high fat intake may contribute to increased carotenoid plasma
concentrations is still unclear. The objective was to examine the degree to which the consumption
of different amounts of both carotenoid-rich foods and fats is associated with plasma carotenoid
concentrations within a Mediterranean lifestyle context (subsample from the PREDIMED-Plus
study baseline) where consumption of F&V and fat is high. The study population was catego rized into four groups according to their self-reported consumption of F&V and fat. Carotenoids
were extracted from plasma samples and analyzed by HPLC-UV-VIS-QqQ-MS/MS. Carotenoid
systemic concentrations were greater in high consumers of F&V than in low consumers of these
foods (+3.04 µmol/L (95% CI: 0.90, 5.17), p-value = 0.005), but circulating concentrations seemed to
decrease when total fat intake was very high (−2.69 µmol/L (−5.54; 0.16), p-value = 0.064). High
consumption of F&V is associated with greater systemic levels of total carotenoids, in particular
when fat intake is low-to-moderate rather than very high. | es |
dc.format | application/pdf | es |
dc.format.extent | 16 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Antioxidants, 10 (3). | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Bioactive compounds | es |
dc.subject | Phytochemicals | es |
dc.subject | Dietary fats | es |
dc.subject | Mediterranean diet | es |
dc.subject | PREDIMED-Plus study | es |
dc.subject | Plasma carotenoids | es |
dc.subject | Matrix effect absorption | es |
dc.subject | Liquid chromatography | es |
dc.subject | Mass spectrometry | es |
dc.title | High fruit and vegetable consumption and moderate fat intake are associated with higher carotenoid concentration in human plasma | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.publisherversion | https://www.mdpi.com/2076-3921/10/3/473 | es |
dc.identifier.doi | 10.3390/antiox10030473 | es |
dc.journaltitle | Antioxidants | es |
dc.publication.volumen | 10 | es |
dc.publication.issue | 3 | es |