dc.creator | Trompier, François | es |
dc.creator | Baumann, Marion | es |
dc.creator | Barrios, Lleonard | es |
dc.creator | Gregoire, Eric | es |
dc.creator | Abend, Michael | es |
dc.creator | Ainsbury, Elizabeth | es |
dc.creator | Domínguez García, Inmaculada | es |
dc.creator | Mateos Pérez, Juan Carlos | es |
dc.creator | Roy, Laurence | es |
dc.date.accessioned | 2022-02-11T08:14:34Z | |
dc.date.available | 2022-02-11T08:14:34Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Trompier, F., Baumann, M., Barrios, L., Gregoire, E., Abend, M., Ainsbury, E.,...,Roy, L. (2017). Investigation of the influence of calibration practices on cytogenetic laboratory performance for dose estimation. International Journal of Radiation Biology, 93 (1), 118-126. | |
dc.identifier.issn | 0955-3002 impreso | es |
dc.identifier.issn | 1362-3095 online | es |
dc.identifier.uri | https://hdl.handle.net/11441/129876 | |
dc.description.abstract | Purpose: In the frame of the QA program of RENEB, an inter-laboratory comparison (ILC) of calibration sources used in biological dosimetry was achieved to investigate the influence of calibration practices and protocols on the results of the dose estimation performance as a first step to harmonization and standardization of dosimetry and irradiation practices in the European biological dosimetry network.
Materials and methods: Delivered doses by irradiation facilities used by RENEB partners were determined with EPR/alanine dosimetry system. Dosimeters were irradiated in the same conditions as blood samples. A short survey was also performed to collect the information needed for the data analysis and evaluate the diversity of practices.
Results: For most of partners the deviation of delivered dose from the targeted dose remains below 10%. Deviations larger than 10% were observed for five facilities out of 21. Origins of the largest discrepancies were identified. Correction actions were evaluated as satisfactory. The re-evaluation of some ILC results for the fluorescence in situ hybridization (FISH) and premature chromosome condensation (PCC) assays has been performed leading to an improvement of the overall performances.
Conclusions: This work has shown the importance of dosimetry in radiobiology studies and the needs of harmonization, standardization in irradiation and dosimetry practices and educational training for biologists using ionizing radiation. | es |
dc.description.sponsorship | European Community’s Seventh Framework Program [grant agreement No. 295513] | es |
dc.format | application/pdf | es |
dc.format.extent | 9 p. | es |
dc.language.iso | eng | es |
dc.publisher | Taylor & Francis | es |
dc.relation.ispartof | International Journal of Radiation Biology, 93 (1), 118-126. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | alanine dosimetry | es |
dc.subject | biological dosimetry | es |
dc.subject | calibration | es |
dc.subject | inter-laboratory comparison | es |
dc.subject | quality assurance | es |
dc.title | Investigation of the influence of calibration practices on cytogenetic laboratory performance for dose estimation | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Biología Celular | es |
dc.relation.projectID | 295513 | es |
dc.relation.publisherversion | http://dx.doi.org/10.1080/09553002.2016.1213455 | es |
dc.identifier.doi | 10.1080/09553002.2016.1213455 | es |
dc.journaltitle | International Journal of Radiation Biology | es |
dc.publication.volumen | 93 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 118 | es |
dc.publication.endPage | 126 | es |
dc.contributor.funder | European Commission (EC) | es |