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dc.creatorÁvila Román, Francisco Javieres
dc.creatorGarcía Gil, Saraes
dc.creatorRodríguez Luna, Azahara Maríaes
dc.creatorMotilva Sánchez, Virginiaes
dc.creatorTalero Barrientos, Elena Mªes
dc.date.accessioned2022-01-04T14:44:39Z
dc.date.available2022-01-04T14:44:39Z
dc.date.issued2021
dc.identifier.citationÁvila Román, F.J., García Gil, S., Rodríguez Luna, A.M., Motilva Sánchez, V. y Talero Barrientos, E.M. (2021). Anti-inflammatory and anticancer effects of microalgal carotenoids. Marine Drugs, 19 (10), 531.
dc.identifier.issn1660-3397es
dc.identifier.urihttps://hdl.handle.net/11441/128654
dc.description.abstractAcute inflammation is a key component of the immune system's response to pathogens, toxic agents, or tissue injury, involving the stimulation of defense mechanisms aimed to removing pathogenic factors and restoring tissue homeostasis. However, uncontrolled acute inflammatory response may lead to chronic inflammation, which is involved in the development of many diseases, including cancer. Nowadays, the need to find new potential therapeutic compounds has raised the worldwide scientific interest to study the marine environment. Specifically, microalgae are considered rich sources of bioactive molecules, such as carotenoids, which are natural isoprenoid pigments with important beneficial effects for health due to their biological activities. Carotenoids are essential nutrients for mammals, but they are unable to synthesize them; instead, a dietary intake of these compounds is required. Carotenoids are classified as carotenes (hydrocarbon carotenoids), such as a- and |3 -carotene, and xanthophylls (oxygenate derivatives) including zeaxanthin, astaxanthin, fucoxanthin, lutein, a- and 3-cryptoxanthin, and canthaxanthin. This review summarizes the present up-to-date knowledge of the anti-inflammatory and anticancer activities of microalgal carotenoids both in vitro and in vivo, as well as the latest status of human studies for their potential use in prevention and treatment of inflammatory diseases and cancer.es
dc.description.sponsorshipUniversidad de Sevilla 2021/00000196es
dc.formatapplication/pdfes
dc.format.extent49 p.es
dc.language.isoenges
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)es
dc.relation.ispartofMarine Drugs, 19 (10), 531.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectCanceres
dc.subjectCarotenoidses
dc.subjectInflammationes
dc.subjectMicroalgaees
dc.subjectOxidative stresses
dc.titleAnti-inflammatory and anticancer effects of microalgal carotenoidses
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Farmacologíaes
dc.relation.projectID2021/00000196es
dc.relation.publisherversionhttps://doi.org/10.3390/md19100531es
dc.identifier.doi10.3390/md19100531es
dc.journaltitleMarine Drugses
dc.publication.volumen19es
dc.publication.issue10es
dc.publication.initialPage531es

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Except where otherwise noted, this item's license is described as: Attribution-NonCommercial-NoDerivatives 4.0 Internacional