dc.creator | Vilchez, Helem H. | es |
dc.creator | Escudero-Sánchez, Rosa | es |
dc.creator | Fernández-Sampedro, Marta | es |
dc.creator | Murillo, Óscar | es |
dc.creator | Auñón, Álvaro | es |
dc.creator | Toro López, María Dolores del | es |
dc.date.accessioned | 2021-09-15T10:38:29Z | |
dc.date.available | 2021-09-15T10:38:29Z | |
dc.date.issued | 2021-04-21 | |
dc.identifier.citation | Vilchez, H.H., Escudero-Sánchez, R., Fernández-Sampedro, M., Murillo, Ó., Auñón, Á. y Del Toro, M.D. (2021). Prosthetic shoulder joint infection by cutibacterium acnes: does rifampin improve prognosis? a retrospective, multicenter, observational study. Antibiotics, 10 (5) | |
dc.identifier.issn | 2079-6382 | es |
dc.identifier.uri | https://hdl.handle.net/11441/125813 | |
dc.description.abstract | This retrospective, multicenter observational study aimed to describe the outcomes of surgical and medical treatment of C. acnes-related prosthetic joint infection (PJI) and the potential benefit of rifampin-based therapies. Patients with C. acnes-related PJI who were diagnosed and treated between January 2003 and December 2016 were included. We analyzed 44 patients with C. acnes-related PJI (median age, 67.5 years (IQR, 57.3–75.8)); 75% were men. The majority (61.4%) had late chronic infection according to the Tsukayama classification. All patients received surgical treatment, and most antibiotic regimens (43.2%) included β-lactam. Thirty-four patients (87.17%) were cured; five showed relapse. The final outcome (cure vs. relapse) showed a nonsignificant trend toward higher failure frequency among patients with previous prosthesis (OR: 6.89; 95% CI: 0.80–58.90) or prior surgery and infection (OR: 10.67; 95% IC: 1.08–105.28) in the same joint. Patients treated with clindamycin alone had a higher recurrence rate (40.0% vs. 8.8%). Rifampin treatment did not decrease recurrence in patients treated with β-lactams. Prior prosthesis, surgery, or infection in the same joint might be related to recurrence, and rifampin-based combinations do not seem to improve prognosis. Debridement and implant retention appear a safe option for surgical treatment of early PJI. | es |
dc.format | application/pdf | es |
dc.format.extent | 13 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Antibiotics, 10 (5) | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Cutibacterium acnes | es |
dc.subject | Prosthetic joint infection | es |
dc.subject | Surgical and medical treatment | es |
dc.title | Prosthetic shoulder joint infection by cutibacterium acnes: does rifampin improve prognosis? a retrospective, multicenter, observational study | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.publisherversion | https://www.mdpi.com/2079-6382/10/5/475 | es |
dc.identifier.doi | 10.3390/antibiotics10050475 | es |
dc.journaltitle | Antibiotics | es |
dc.publication.volumen | 10 | es |
dc.publication.issue | 5 | es |