dc.creator | Montull, Beatriz | es |
dc.creator | Menéndez, Rosario | es |
dc.creator | Torres, Antoni | es |
dc.creator | Reyes, Soledad | es |
dc.creator | Méndez, Raúl | es |
dc.creator | Alfageme Michavila, Inmaculada | es |
dc.creator | Ruiz Manzano, Juan | es |
dc.date.accessioned | 2021-08-27T10:24:40Z | |
dc.date.available | 2021-08-27T10:24:40Z | |
dc.date.issued | 2016-01-04 | |
dc.identifier.citation | Montull, B., Menéndez, R., Torres, A., Reyes, S., Méndez, R., Alfageme Michavila, I. y Ruiz Manzano, J. (2016). Predictors of Severe Sepsis among Patients Hospitalized for Community-Acquired Pneumonia. PLoS ONE, 11 (1), art.n.e0145929. | |
dc.identifier.issn | 1932-6203 (electrónica) | es |
dc.identifier.uri | https://hdl.handle.net/11441/125198 | |
dc.description.abstract | Background
Severe sepsis, may be present on hospital arrival in approximately one-third of patients with
community-acquired pneumonia (CAP).
Objective
To determine the host characteristics and micro-organisms associated with severe sepsis
in patients hospitalized with CAP.
Results
We performed a prospective multicenter cohort study in 13 Spanish hospital, on 4070 hospitalized CAP patients, 1529 of whom (37.6%) presented with severe sepsis. Severe sepsis
CAP was independently associated with older age (>65 years), alcohol abuse (OR, 1.31;
95% CI, 1.07–1.61), chronic obstructive pulmonary disease (COPD) (OR, 1.75; 95% CI,
1.50–2.04) and renal disease (OR, 1.57; 95% CI, 1.21–2.03), whereas prior antibiotic treatment was a protective factor (OR, 0.62; 95% CI, 0.52–0.73). Bacteremia (OR, 1.37; 95% CI,
1.05–1.79), S pneumoniae (OR, 1.59; 95% CI, 1.31–1.95) and mixed microbial etiology
(OR, 1.65; 95% CI, 1.10–2.49) were associated with severe sepsis CAP.
Conclusions
CAP patients with COPD, renal disease and alcohol abuse, as well as those with CAP due
to S pneumonia or mixed micro-organisms are more likely to present to the hospital with
severe sepsis. | es |
dc.description.sponsorship | PII (Programme of research of SEPAR) in respiratory infection | es |
dc.description.sponsorship | CIBERES (Centro de investigación en red de enfermedades respiratorias) an initiative of ISCIII (Instituto de Salud Carlos III) | es |
dc.description.sponsorship | Beca SEPAR (Sociedad Española de Neumología y Cirugía torácica) (2006/0237) | es |
dc.description.sponsorship | Beca de la Consellería Sanitat Comunidad Valenciana (2007/ 0059) | es |
dc.format | application/pdf | es |
dc.format.extent | 9 p. | es |
dc.language.iso | eng | es |
dc.publisher | Public Library of Science | es |
dc.relation.ispartof | PLoS ONE, 11 (1), art.n.e0145929. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Sepsis | es |
dc.subject | Microbiological studies | es |
dc.subject | Severe sepsis | es |
dc.subject | Community acquired pneumonia | es |
dc.subject | CAP | es |
dc.title | Predictors of Severe Sepsis among Patients Hospitalized for Community-Acquired Pneumonia | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.projectID | 2006/0237 | es |
dc.relation.projectID | 2007/0059 | es |
dc.relation.publisherversion | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145929 | es |
dc.identifier.doi | 10.1371/journal.pone.0145929 | es |
dc.journaltitle | PLoS ONE | es |
dc.publication.volumen | 11 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | art.n.e0145929 | es |