Artículos (Instituto de Biomedicina de Sevilla (IBIS)): Envíos recientes
Mostrando ítems 161-180 de 303
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A variant in the MICA gene is associated with liver fbrosis progression in chronic hepatitis C through TGF-β1 dependent mechanisms
(Nature Research, 2019-02-05)Hepatocarcinogenesis is tightly linked to liver fibrosis. Recently, two GWAS variants, MICA rs2596542 and DEPDC5 rs1012068 ...
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Phosphorylated-insulin growth factor I receptor (p-IGF1R) and metalloproteinase-3 (MMP3) expression in advanced gastrointestinal stromal tumors (GIST). A GEIS 19 study
(BMC, 2016-06-29)Background: Most GISTs have mutations in KIT or PDGFRA. Patients with advanced GIST with KIT exon 9, PDGFRA mutation or ...
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Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuronal and oligodendrocyte survival
(Dove Medical Press Ltd., 2015)Chronic hypoxemia, as evidenced in de-acclimatized high-altitude residents or in patients with chronic obstructive ...
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Neurocognitive Function in Acromegaly after Surgical Resection of GH-Secreting Adenoma versus Naïve Acromegaly
(Elsevier, 2013-04-04)Patients with active untreated acromegaly show mild to moderate neurocognitive disorders that are associated to chronic ...
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Integrated molecular signaling involving mitochondrial dysfunction and alteration of cell metabolism induced by tyrosine kinase inhibitors in cancer
(Elsevier, 2020-03-16)Cancer cells have unlimited replicative potential, insensitivity to growth-inhibitory signals, evasion of apoptosis,cellular ...
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Changing Trends in the Epidemiology and Risk Factors of Pneumocystis Pneumonia in Spain
(2019-10-04)Objective: The information about the epidemiology of Pneumocystis pneumonia (PcP) in Europe is scarce, and in Spain there ...
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Trends in the prevalence and distribution of HTLV-1 and HTLV-2 infections in Spain
(BMC, 2012)Background Although most HTLV infections in Spain have been found in native intravenous drug users carrying HTLV-2, the ...
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Parasites and malignancies, a review, with emphasis on digestive cancer induced by Cryptosporidium parvum (Alveolata: Apicomplexa)
(EDP Open, 2012-05-15)The International Agency for Research on Cancer (IARC) identifies ten infectious agents (viruses, bacteria, parasites) ...
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No difference in effectiveness of treatment simplification to boosted or unboosted atazanavir plus lamivudine in virologically suppressed in HIV-1-infected patients
(Public Library of Science, 2018-09-20)Background Simplification strategies of antiretroviral treatment represent effective tools for the reduction of drug-induced ...
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Liver Fibrosis, Host Genetic and Hepatitis C Virus Related Parameters as Predictive Factors of Response to Therapy against Hepatitis C Virus in HIV/HCV Coinfected Patients
(Public Library of Science, 2014-07-11)Objective: To establish the role of liver fibrosis as a predictive tool of response to pegylated interferon alpha (Peg-IFN) ...
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Clinical and Virological Efficacy of Etravirine Plus Two Active Nucleos(t)ide Analogs in an Heterogeneous HIV-Infected Population
(Public Library of Science, 2014-05-16)Etravirine (ETV) is recommended in combination with a boosted protease inhibitor plus an optimized background regimen for ...
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Differences in HCV Viral Decline between Low and Standard-Dose Pegylated-Interferon-Alpha-2a with Ribavirin in HIV/HCV Genotype 3 Patients
(Public Library of Science, 2012-11-08)Background: The aim of the study was to analyze the different impact of standard and low-dose Peg-IFN-a2a/RBV therapies on ...
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HIF-2a is essential for carotid body development and function
(eLife Sciences Publications, 2018-04-19)Mammalian adaptation to oxygen flux occurs at many levels, from shifts in cellular metabolism to physiological adaptations ...
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Two for the Price of One: A Neuroprotective Chaperone Kit within NAD Synthase Protein NMNAT2
(Public Library of Science, 2016-07-25)One of the most fascinating properties of the brain is the ability to function smoothly across decades of a lifespan. ...
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Role of aquaporins in cell proliferation: What else beyond water permeability?
(Taylor & Francis Open Access, 2016-02-21)In addition to the extensive data demonstrating the importance of mammalian AQPs for the movement of water and some small ...
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Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound
(Public Library of Science, 2012-05-18)Aquaporins (AQPs) are membrane channels that conduct water and small solutes such as glycerol and are involved in many ...
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Expression of PROKR1 and PROKR2 in Human Enteric Neural Precursor Cells and Identification of Sequence Variants Suggest a Role in HSCR
(Public Library of Science, 2011-08-12)Background: The enteric nervous system (ENS) is entirely derived from neural crest and its normal development is regulated by ...
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Preimplantation Genetic Diagnosis for Myotonic Dystrophy Type 1 and Analysis of the Effect of the Disease on the Reproductive Outcome of the Affected Female Patients
(Hindawi, 2017-11-14)Myotonic dystrophy type 1 (DM1) is the most common adult muscular dystrophy and presents an autosomal dominant inheritance. ...
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Co-segregation of a homozygous SMN1 deletion and a heterozygous PMP22 duplication in a patient
(Wiley Open Access, 2016-07-03)Despite co-segregation of two different genetic neurological disorders within a family is rare, clinicians should take ...
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Next-generation-based targeted sequencing as an efficient tool for the study of the genetic background in Hirschsprung patients
(BMC, 2015-10-05)Background: The development of next-generation sequencing (NGS) technologies has a great impact in the human variation ...