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Browsing Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) by Author "González Prieto, Román"
Now showing items 1-6 of 6
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Article
Application of flow focusing to the break-up of a magnetite suspension jet for the production of paramagnetic microparticles
Martín Banderas, Lucía; González Prieto, Román; Rodríguez Gil, Alfonso; Fernández Arévalo, María Mercedes; Flores Mosquera, María; Chávez de Diego, Sebastián; Gañán-Calvo, Alfonso M. (2011)Paramagnetic particles offer an extensive improvement in the magnetic separation or purification of a wide variety of ...
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Article
BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis
Salas Lloret, Daniel; García Rodríguez, Néstor; Soto Hidalgo, Emily; González Vinceiro, Lourdes; Espejo Serrano, Carmen; Giebel, Lisanne; Huertas Sánchez, Pablo; González Prieto, Román (Nature Research, 2024-05-20)Deficiencies in the BRCA1 tumor suppressor gene are the main cause of hereditary breast and ovarian cancer. BRCA1 is ...
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Article
Non-recombinogenic roles for Rad52 in translesion synthesis during DNA damage tolerance
Cano Linares, María Isabel; Yáñez Vilches, Aurora; García Rodríguez, Néstor; Barrientos Moreno, Marta; González Prieto, Román; San Segundo, Pedro; Ulrich, Helle D.; Prado, Félix (Wiley-Blackwell, 2021)DNA damage tolerance relies on homologous recombination (HR) and translesion synthesis (TLS) mechanisms to fill in the ...
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Article
Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability
Yáñez Vilches, Aurora; Romero, Antonia M.; Barrientos Moreno, Marta; Cruz, Esther; González Prieto, Román; Sharma, Sushma; Vertegaal, Alfred C.O.; Prado, Félix (Public Library of Science, 2024-05-22)The helicase MCM and the ribonucleotide reductase RNR are the complexes that provide the substrates (ssDNA templates and ...
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Article
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy
Nguyen, Binh An; Singh, Virender; Afrin, Shumaila; Yakubovska, Anna; Wang, Lanie; Ahmed, Yasmin; González Prieto, Román; Saelices, Lorena (Nature Research, 2024-01-17)ATTR amyloidosis is caused by the deposition of transthyretin in the form of amyloid fibrils in virtually every organ of ...
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Article
UBE2D3 Facilitates NHEJ by Orchestrating ATM Signalling through Multi-level Control of RNF168
Yalçin, Zeliha; Lam, Shiu Yeung; Peuscher, Marieke H.; van der Torre, Jaco; Zhu, Sha; Iyengar, Prasanna V.; Salas Lloret, Daniel; de Krijger, Inge; Moatti, Nathalie; van der Lugt, Ruben; González Prieto, Román; Jacobs, Jacqueline J.L. (Springer Nature, 2024)Maintenance of genome integrity requires tight control of DNA damage response (DDR) signalling and repair, with phosphorylation ...