Listar Artículos (Química Orgánica y Farmacéutica) por fecha de publicación
Mostrando ítems 81-100 de 171
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Reversible pH-sensitive chitosan-based hydrogels. Influence of dispersion composition on rheological properties and sustained drug delivery
(MDPI, 2018)The present work deals with the synthesis of micro-structured biomaterials based on chitosan (CTS) for their applications ...
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Nanocomposites of Microbial Polyglutamic Acid and Nanoclays Compatibilized by Organophosphonium Surfactants
(Wiley, 2018)Ionic coupling of bacterial poly(γ-glutamic acid) (PGGA) with alkyltrimethylphosphonium surfactants is reported to render ...
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Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside
(Wiley, 2018)Several clinically useful anticancer drugs selectively kill cancer cells by inducing DNA damage; the genomic instability ...
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Glucose-nucleobase pairs within DNA: Impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies
(Royal Society of Chemistry, 2018)Recently, we studied glucose-nucleobase pairs, a binding motif found in aminoglycoside-RNA recognition. DNA duplexes with ...
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Metal-free catalyzed ring-opening polymerization and block copolymerization of ω-pentadecalactone using amino-ended initiators
(Elsevier, 2018)Metal-free catalysis was successfully applied to polymerize ω-pentadecalactone (PDL) by ring-opening polymerization (ROP) ...
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Comparison of the anti-angiogenic potential of hydroxytyrosol and five derivatives
(Royal Society of Chemistry, 2018)Hydroxytyrosol is a phenolic compound present in extra virgin olive oil, either in free form or as derivatives, and related ...
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NMR study on the stabilization and chiral discrimination of sulforaphane enantiomers and analogues by cyclodextrins
(Elsevier, 2018)Sulforaphane (SFN), a phytochemical isolated from broccoli, is an important antitumoral compound with additional beneficial ...
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Hydrolytic degradation of D-mannitol-based polyurethanes
(Elsevier, 2018)The capacity of redox D-mannitol-based polyurethanes to modulate the glutathione response under physiological conditions, ...
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Validation of Smart Nanoparticles as Controlled Drug Delivery Systems: Loading and pH-Dependent Release of Pilocarpine
(American Chemical Society, 2018-01-11)Micelles are good devices for use as controlled drug delivery systems because they exhibit the ability to protect the ...
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An Efficient and Practical Method for the Enantioselective Synthesis of Tertiary Trifluoromethyl Carbinols
(Wiley Online Library, 2018-03)An efficient sulfinamide/olefin based chiral ligand, MetSulfolefin, has been developed for the enantioselective rhodium-catalysed ...
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Loading studies of the anticancer drug camptothecin into dual stimuli-sensitive nanoparticles. Stability scrutiny
(Elsevier, 2018-10-25)In recent years, the preparation of valuable drug delivery systems (DDS) from self-assembled amphiphilic copolymers has ...
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Investigation of TNBC in vitro Antiproliferative Effects of Versatile Pirrolo[1,2-a]quinoxaline Compounds
(Frontiers Media, 2019)he triple-negative breast cancer (TNBC) is characterized by a more aggressive nature and poorer prognosis, nowadays none ...
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Synthesis and Characterization of New Biocompatible Amino Amphiphilic Compounds Derived from Oleic Acid as Nanovectors for Drug Delivery
(MDPI, 2019)Amphiphilic molecules have been actively explored as promising materials in the field of bio and nanotechnology. These ...
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Design of highly stabilized nanocomposite inks based on biodegradable polymer-matrix and gold nanoparticles for Inkjet Printing
(Nature Research, 2019)Nowadays there is a worldwide growing interest in the Inkjet Printing technology owing to its potentially high levels of ...
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Antioxidant and Anti-Inflammatory Activities of Flavanones from Glycyrrhiza glabra L. (licorice) Leaf Phytocomplexes: Identification of Licoflavanone as a Modulator of NF-kB/MAPK Pathway
(MDPI, 2019)Inflammation represents an adaptive response generated by injuries or harmful stimuli. Natural remedies represent an ...
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Synthesis and Characterization of Elongated-Shaped Silver Nanoparticles as a Biocompatible Anisotropic SERS Probe for Intracellular Imaging: Theoretical Modeling and Experimental Verification
(MDPI, 2019)Progress in the field of biocompatible SERS nanoparticles has promising prospects for biomedical applications. In this ...
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Experimental model design: exploration and optimization of customized polymerization conditions for the preparation of targeted smart materials by the Diels Alder click reaction
(Royal Society of Chemistry, 2019)The experimental model design proposed herein has proved to be an indispensable tool to rapidly and easily elucidate the ...
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Nanostructured Chitosan-Based Biomaterials for Sustained and Colon-Specific Resveratrol Release
(MDPI, 2019-01)In the present work, we demonstrate the preparation of chitosan-based composites as vehicles of the natural occurring ...
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Comprehensive Toxicity Assessment of PEGylated Magnetic Nanoparticles for in vivo applications
(Elsevier, 2019-05-01)Magnetic nanoparticles (MNPs) represent one of the greatest promises for the development of a new generation of diagnostic ...
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Steric Tuning of Sulfinamide/Sulfoxides as Chiral Ligands with C1, Pseudo-meso, and Pseudo‑C2 Symmetries: Application in Rhodium(I)-Mediated Arylation
(ACS, 2019-07-31)A new family of sulfinamide/sulfoxide derivatives was synthesized as chiral bidentate ligands by stereoselective additions ...