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A Predictive Model for Selecting Patients with HCV Genotype 3 Chronic Infection with a High Probability of Sustained Virological Response to Peginterferon Alfa-2a/Ribavirin
Background Access to direct-acting antiviral agents (DAAs) is restricted in some settings; thus, the Euro pean Association for the Study of the Liver recommends dual peginterferon/ribavirin (PegIFN/RBV) therapy wherever ...
Reduced sTWEAK and Increased sCD163 Levels in HIVInfected Patients: Modulation by Antiretroviral Treatment, HIV Replication and HCV Co-Infection
(Public Library of Science, 2014-03-04)
Background: Patients infected with the human immunodeficiency virus (HIV) have an increased risk of cardiovascular disease due to increased inflammation and persistent immune activation. CD163 is a macrophage scavenger ...
Simvastatin and metformin inhibit cell growth in hepatitis C virus infected cells via mTOR increasing PTEN and autophagy
Hepatitis C virus (HCV) infection has been related to increased risk of development of hepa tocellular carcinoma (HCC) while metformin (M) and statins treatment seemed to protect against HCC development. In this work, we ...