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Mostrando ítems 31-40 de 108
Artículo
Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles
(Willey, 2022)
Background and Aims We previously identified subsets of patients with NAFLD with different metabolic phenotypes. Here we align metabolomic signatures with cardiovascular disease (CVD) and genetic risk factors. Approach ...
Artículo
Co-expression gene network analysis reveals novel regulatory pathways involved in porto-sinusoidal vascular disease
(Elsevier, 2021-10)
Background & Aims Porto-sinusoidal vascular disease (PSVD) is a rare vascular liver disease of unknown etiology that causes portal hypertension. It usually affects young individuals and shortens live expectancy. The ...
Artículo
Implementing personalized medicine in covid-19 in andalusia: an opportunity to transform the healthcare system
(MDPI, 2021-05-26)
The COVID-19 pandemic represents an unprecedented opportunity to exploit the advantages of personalized medicine for the prevention, diagnosis, treatment, surveillance and management of a new challenge in public health. ...
Artículo
New therapeutic perspectives in non-alcoholic steatohepatitis
(Elsevier, 2018-02-23)
Management of non-alcoholic steatohepatitis is focused on restitution of metabolic derangement, weight loss and drugs able to improve steatosis, ballooning and fibrosis. Life-style interventions based on Mediterranean ...
Artículo
Management of NAFLD patients with advanced fibrosis
(Wiley-Blackwell, 2021-06-21)
The prevalence of non alcoholic fatty liver disease (NAFLD) has increased to 25% in the general population and could double by 2030. Liver fibrosis is the main indicator of morbidity and mortality and recent estimations ...
Artículo
Disease burden and economic impact of diagnosed non-alcoholic steatohepatitis in five European countries in 2018: A cost-of-illness analysis
(Wiley-Blackwell, 2021)
Background and aims: Non-alcoholic steatohepatitis (NASH) is a chronic disease that can progress to end-stage liver disease (ESLD). A large proportion of early-stage NASH patients remain undiagnosed compared to those ...
Artículo
Metformin inhibits glutaminase activity and protects against hepatic encephalopathy
(2012)
Aim: To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective cohort of diabetic cirrhotic patients. To analyze the impact of metformin on glutaminase activity and ...
Artículo
Propuesta de nueva denominación: esteatosis hepática metabólica (EHmet)
(Arán Ediciones, S.L., 2021)
El nombre de una enfermedad no sigue ningún protocolo definido y es habitual la aceptación por parte de la comunidad científica de diversas variantes en función de las costumbres de cada lugar. Hay ejemplos de entidades ...
Artículo
Novel genes and sex differences in COVID-19 severity
(OXFORD UNIV PRESS, 2022)
Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus disease 2019 (COVID-19) positive cases with an extensive clinical information that were recruited from 34 hospitals across Spain (SCOURGE ...
Artículo
Extracellular Vesicles as Biomarkers in Liver Disease
(MDPI, 2022-12-19)
Extracellular vesicles (EVs) are membrane-derived vesicles released by a variety of cell types, including hepatocytes, hepatic stellate cells, and immune cells in normal and pathological conditions. Depending on their ...