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Artículo
Virulence role of the outer membrane protein CarO in carbapenem-resistant Acinetobacter baumannii
(Taylor and Francis, 2020)
Novel approaches to treat carbapenem-resistant Acinetobacter baumannii (CRAB) infections are urgently needed and anti-virulence drugs represent promising alternatives, but our knowledge on potential targets is scarce. We ...
Artículo
Impact of an antimicrobial stewardship program on the incidence of carbapenem resistant gram-negative bacilli: an interrupted time-series analysis
(MDPI, 2021)
Carbapenem-resistant Gram-negative bacilli (CR-GNB) are a critical public health threat, and carbapenem use contributes to their spread. Antimicrobial stewardship programs (ASPs) have proven successful in reducing antimicrobial ...
Artículo
Step-up and step-down treatment approaches for COPD: a holistic view of progressive therapies
(DOVE MEDICAL PRESS LTD, 2021-07-12)
Recent advances in inhaled drugs and a clearer definition of the disease have made the task of managing COPD more complex. Different proposals have been put forward which combine all the available treatments and the ...
Artículo
Clinical characterization and outcomes of 85 patients with neurosarcoidosis
(NATURE PUBLISHING GROUP, 2021-07-02)
To analyze the frequency and clinical phenotype of neurosarcoidosis (NS) in one of the largest nationwide cohorts of patients with sarcoidosis reported from southern Europe. NS was evaluated according to the Diagnostic ...
Artículo
Modifications in the distribution of met-enkephalin in the cat spinal cord after administration of clonidine. An immunocytochemical study
(Universidad de Murcia. Departamento de Biología Celular e Histología, 1998-11-02)
We have studied the modifications in the distribution of methionine-enkephalin in the cat spinal cord after intravenous or intrathecal administration of clonidine by using an immunocytochemical technique. In animals not ...
Artículo
Programa de Reducción de la Infección Quirúrgica del Observatorio de Infección en Cirugía (PRIQ-O). Documento de priorización y consenso Delphi de recomendaciones para la prevención de la infección de localización quirúrgica
(Elsevier Doyma, 2023-04)
La infección de localización quirúrgica es la complicación más frecuente y más evitable de la cirugía, pero las guías clínicas para su prevención tienen un seguimiento insuficiente. Presentamos los resultados de un consenso ...
Artículo
Phase III Trial of Adjuvant Capecitabine After Standard Neo-/Adjuvant Chemotherapy in Patients With Early Triple-Negative Breast Cancer (GEICAM/2003-11_CIBOMA/2004-01)
(American Society of Clinical Oncology, 2020)
PURPOSE Operable triple-negative breast cancers (TNBCs) have a higher risk of relapse than non-TNBCs with standard therapy. The GEICAM/2003-11_CIBOMA/2004-01 trial explored extended adjuvant capecitabine after completion ...
Artículo
Characterization of COPD admissions during the first COVID-19 outbreak
(Dove Medical Press LDT, 2021-06-03)
Purpose: Exacerbations of COPD (ECOPD) are a frequent cause of hospitalization that seemed to ameliorate during the COVID outbreak. We aimed to evaluate the clinical characteristics of COPD-related hospital admissions and ...
Artículo
Isolated Limb Perfusion for Malignant Melanoma: Systematic Review on Effectiveness and Safety
(Oxford Academic, 2010)
Background. Isolated limb perfusion (ILP) involves the administration of chemotherapy drugs directly into a limb involved by locoregional metastases. Unresectable locally advanced melanoma of the limbs represents one of ...
Artículo
Gestión clínica en las unidades de nutrición
(Aula Medica Ediciones, 2021)
Introducción: la gestión clínica es un elemento de excelencia en la práctica de la nutricion clínica que está menos reconocido que otros, como la formación continuada o la investigación. Objetivos: el objetivo de este ...