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Artículo
Extracellular Vesicles as Biomarkers in Liver Disease
(MDPI, 2022-12-19)
Extracellular vesicles (EVs) are membrane-derived vesicles released by a variety of cell types, including hepatocytes, hepatic stellate cells, and immune cells in normal and pathological conditions. Depending on their ...
Artículo
Sofosbuvir improves HCV-induced insulin resistance by blocking IRS1 degradation
(WILEY, 2021-01-12)
In the present study, we have demonstrated that sofos buvir (SOF) treatment improves systemic insulin resis tance in hepatitis C virus (HCV)-patients, and, for the first time, revealed which molecular mechanisms are ...