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Mostrando ítems 1-10 de 17
Artículo
Virulence role of the outer membrane protein CarO in carbapenem-resistant Acinetobacter baumannii
(Taylor and Francis, 2020)
Novel approaches to treat carbapenem-resistant Acinetobacter baumannii (CRAB) infections are urgently needed and anti-virulence drugs represent promising alternatives, but our knowledge on potential targets is scarce. We ...
Artículo
Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems
(American Society for Biochemistry and Molecular Biology, Inc., 2017-04-03)
Pathogenic Acinetobacter species, including Acinetobacter baumannii and Acinetobacter nosocomialis, are opportunistic human pathogens of increasing relevance worldwide. Although their mechanisms of drug resistance are ...
Artículo
Clinical validation of a real-time polymerase chain reaction assay for rapid detection of Acinetobacter baumannii colonization
(W B SAUNDERS CO LTD, 2016)
Real-time polymerase chain reaction (PCR)-based approaches have not been assessed in terms of their ability to detect patients colonized by Acinetobacter baumannii during active surveillance. This prospective, double-blind ...
Artículo
Phenotypic and molecular characterizations of carbapenem-resistant Acinetobacter baumannii isolates collected within the EURECA study
(Elsevier Science, 2021)
Multi-drug-resistant Acinetobacter baumannii isolates are key pathogens that contribute to the global bur den of antimicrobial resistance. This study aimed to investigate the phenotypic and molecular character istics of ...
Artículo
Immunization with Lipopolysaccharide-Deficient Whole Cells Provides Protective Immunity in an Experimental Mouse Model of Acinetobacter baumannii Infection
(2014)
The increasing clinical importance of infections caused by multidrug resistant Acinetobacter baumannii warrants the development of novel approaches for prevention and treatment. In this context, vaccination of certain ...
Artículo
European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine)
(Wiley-Blackwell, 2022)
Scope: These ESCMID guidelines address the targeted antibiotic treatment of third-generation cepha losporin-resistant Enterobacterales (3GCephRE) and carbapenem-resistant Gram-negative bacteria, focusing on the effectiveness ...
Artículo
Synergistic Activity of Niclosamide in Combination With Colistin Against Colistin-Susceptible and Colistin-Resistant Acinetobacter baumannii and Klebsiella pneumoniae
(Frontiers Research Foundation, 2018-10-03)
Colistin is among the few antibiotics effective against multidrug-resistant Acinetobacter baumannii and Klebsiella pneumoniae clinical isolates. However, in the last few years, colistin-resistant A. baumannii and K. ...
Artículo
Positive Predictive Value of Leeds Acinetobacter Medium for Environmental Surveillance of Acinetobacter baumannii
(American Society of Microbiology, 2011)
Infections caused by Acinetobacter baumannii often occur in outbreaks during which the bacteria are spread through contact with clinical personnel harboring the bacteria and from colonized hospital equipment (2). Environmental ...
Artículo
Epidemiologic and Clinical Impact of Acinetobacter baumannii Colonization and Infection: A Reappraisal
(Lippincott Williams & Wilkins, 2014)
Acinetobacter baumannii is one of the most important antibiotic-resistant nosocomial bacteria. We investigated changes in the clinical and molecular epidemiology of A. baumannii over a 10-year period. We compared the data ...
Artículo
Inhibition of LpxC Increases Antibiotic Susceptibility in Acinetobacter baumannii
(American Society for Microbiology, 2016-08)
LpxC inhibitors have generally shown poor in vitro activity against Acinetobacter baumannii. We show that the LpxC inhibitor PF-5081090 inhibits lipid A biosynthesis, as determined by silver staining and measurements of ...