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Mostrando ítems 1-10 de 31
Artículo
Step-up and step-down treatment approaches for COPD: a holistic view of progressive therapies
(DOVE MEDICAL PRESS LTD, 2021-07-12)
Recent advances in inhaled drugs and a clearer definition of the disease have made the task of managing COPD more complex. Different proposals have been put forward which combine all the available treatments and the ...
Artículo
Characterization of COPD admissions during the first COVID-19 outbreak
(Dove Medical Press LDT, 2021-06-03)
Purpose: Exacerbations of COPD (ECOPD) are a frequent cause of hospitalization that seemed to ameliorate during the COVID outbreak. We aimed to evaluate the clinical characteristics of COPD-related hospital admissions and ...
Artículo
A Comparative Study between Spanish and British SARS-CoV-2 Variants
(MDPI, 2021-11-16)
The study of the interaction between the SARS-CoV-2 spike protein and the angiotensin-converting enzyme 2 (ACE2) receptor is key to understanding binding affinity and stability. In the present report, we sought to investigate ...
Artículo
Dysfunction in the Cystic Fibrosis Transmembrane Regulator in Chronic Obstructive Pulmonary Disease as a Potential Target for Personalised Medicine
(MDPI, 2021-10-10)
In recent years, numerous pathways were explored in the pathogenesis of COPD in the quest for new potential therapeutic targets for more personalised medical care. In this context, the study of the cystic fibrosis transmembrane ...
Artículo
Recomendaciones SEPAR sobre la vacuna COVID-19 en las enfermedades respiratorias
(Elsevier, 2021-04)
La Sociedad Espanola de Neumología y Cirugía Torácica (SEPAR) ha elaborado este documento de reco mendaciones sobre la vacuna para la COVID-19 en las enfermedades respiratorias, con el objetivo de ayudar al personal ...
Artículo
Cigarette Smoke Decreases the Maturation of Lung Myeloid Dendritic Cells
(Public Library of Science, 2016-04-08)
Background Conflicting data exist on the role of pulmonary dendritic cells (DCs) and their maturation in patients with chronic obstructive pulmonary disease (COPD). Herein, we investigated whether disease severity and ...
Artículo
Systematic evaluation of plasma signaling cascades by functional proteomics approaches SARS-CoV-2 infection as model
(Wiley, 2022-09-28)
Purpose Acute phase reactants (APRs) play a critical role in inflammation. The difference in their physiological functions or the different dynamic ranges of these proteins in plasma makes it difficult to detect them ...
Artículo
Overexpression of aquaporin-1 in lung adenocarcinomas and pleural mesotheliomas
(2011-04-01)
Aquaporin-1 (AQP1) is the main water channel responsible for water transport through many epithelia and endothelia. The latest evidence pointed toward an important role of this protein also in gas permeation, angiogenesis, ...
Artículo
Artículo
Testing for alpha-1 antitrypsin in COPD in outpatient respiratory clinics in Spain: A multilevel, cross-sectional analysis of the EPOCONSUL study
(Public Library of Science, 2018-06-28)
Background Alpha-1 antitrypsin deficiency (AATD) is the most common hereditary disorder in adults, but is under-recognized. In Spain, the number of patients diagnosed with AATD is much lower than expected according to ...