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Mostrando ítems 1-10 de 37
Artículo
Impact of an antimicrobial stewardship program on the incidence of carbapenem resistant gram-negative bacilli: an interrupted time-series analysis
(MDPI, 2021)
Carbapenem-resistant Gram-negative bacilli (CR-GNB) are a critical public health threat, and carbapenem use contributes to their spread. Antimicrobial stewardship programs (ASPs) have proven successful in reducing antimicrobial ...
Artículo
Aripiprazole as a candidate treatment of COVID-19 identified through genomic analysis
(Frontiers Media SA, 2021)
Background: Antipsychotics modulate expression of inflammatory cytokines and inducible inflammatory enzymes. Elopiprazole (a phenylpiperazine antipsychotic drug in phase 1) has been characterized as a therapeutic drug to ...
Artículo
Clinical validation of a real-time polymerase chain reaction assay for rapid detection of Acinetobacter baumannii colonization
(W B SAUNDERS CO LTD, 2016)
Real-time polymerase chain reaction (PCR)-based approaches have not been assessed in terms of their ability to detect patients colonized by Acinetobacter baumannii during active surveillance. This prospective, double-blind ...
Artículo
BIChromET: A Chromogenic Culture Medium for Detection of Piperacillin/Tazobactam and Cefepime Resistance in Pseudomonas aeruginosa
(MDPI, 2023)
Objectives: The BIChromET selective medium for detecting piperacillin-tazobactam (TZP) and cefepime (FEP) resistant Pseudomonas aeruginosa was developed. Methods: The performance of this medium was first evaluated using a ...
Artículo
Neurological manifestations of COVID-19 in adults and children
(Oxford University Press, 2023)
Different neurological manifestations of coronavirus disease 2019 (COVID-19) in adults and children and their impact have not been well characterized. We aimed to determine the prevalence of neurological manifestations ...
Artículo
A step forward in antibiotic use and resistance monitoring: a quarterly surveillance system pilot in 11 European Union/European Economic Area countries, September 2017 to May 2020
(European Centre for Disease Prevention and Control, 2022-11-17)
Background Surveillance of antimicrobial resistance (AMR) and antimicrobial use (AMU) in Europe is currently annual. Aim To study the feasibility and scalability of a quarterly AMR/AMU surveillance system in the ...
Artículo
Clinical Features of Infections and Colonization by Acinetobacter Genospecies 3
(American Society for Microbiology, 2010-12)
Two hundred twenty-one isolates of Acinetobacter baumannii and 15 of Acinetobacter genospecies 3 (AG3) were consecutively collected in a 30-day period during the nationwide project GEIH-Ab2000. Nosocomial acquisition (P = ...
Artículo
Risk Factors and Prognosis of Nosocomial Bloodstream Infections Caused by Extended-Spectrum-B-Lactamase-Producing Escherichia coli
(American Society for Microbiology, 2010-05)
Extended-spectrum-B-lactamase (ESBL)-producing Escherichia coli (ESBLEC) is an increasing cause of community and nosocomial infections worldwide. However, there is scarce clinical information about nosocomial bloodstream ...
Artículo
Pharmacokinetics and safety of aztreonam/avibactam for the treatment of complicated intra-abdominal infections in hospitalized adults: results from the REJUVENATE study
(Oxford University Press, 2020)
Objectives: To investigate pharmacokinetics (PK) and safety (primary objectives) and efficacy (secondary objective) of the investigational monobactam/b-lactamase inhibitor combination aztreonam/avibactam in patients with ...
Artículo
Carbapenem Combinations for Infections Caused by Carbapenemase-Producing Pseudomonas aeruginosa: Experimental In Vitro and In Vivo Analysis
(MDPI, 2022-09-07)
In the context of difficult-to-treat carbapenem-resistant Pseudomonas aeruginosa infections, we evaluated imipenem, meropenem, and doripenem combinations against eleven carbapenemase-producing P. aeruginosa isolates. ...