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Mostrando ítems 971-980 de 1014
Artículo
A phase IIa active-comparator-controlled study to evaluate the efficacy and safety of efinopegdutide in patients with non-alcoholic fatty liver disease
(Elsevier, 2023)
Background & Aims: This study assessed the effects of the glucagon-like peptide-1 (GLP-1)/glucagon receptor co-agonist efinopegdutide relative to the selective GLP-1 receptor agonist semaglutide on liver fat content (LFC) ...
Artículo
Impact of disease burden and late loss of B cell aplasia on the risk of relapse after CD19 chimeric antigen receptor T Cell (Tisagenlecleucel) infusion in pediatric and young adult patients with relapse/refractory acute lymphoblastic leukemia: role of B-cell monitoring
(Frontiers Media S.A., 2024-01-16)
Introduction: Loss of B-cell aplasia (BCA) is a well-known marker of functional loss of CD19 CAR-T. Most relapses and loss of BCA occur in the first months after CD19 CAR-T infusion. In addition, high tumor burden (HTB) ...
Artículo
Outcomes after intensive chemotherapy for secondary and myeloid-related changes acute myeloid leukemia patients aged 60 to 75 years old: a retrospective analysis from the PETHEMA registry
(Ferrata Storti Foundation, 2024)
Treatment options for patients with secondary acute myeloid leukemia (sAML) and AML with myeloid-related changes (AMLMRC) aged 60 to 75 years are scarce and unsuitable. A pivotal trial showed that CPX-351 improved complete ...
Artículo
Oportunistic diagnosis based on age and hepatitis C virus clearance: an essential step to improve the overall health of the liver
(Aran Ediciones S.A., 2023)
Back in January 2022, a The Lancet-European Association for the Study of the Liver (EASL) Commission on the impact of liver disorders in the European region commissioned by the World Health Organization (WHO) ...
Artículo
Management of chronic liver disease-associated severe thrombocytopenia in Spain: a view from the experts
(Aran Ediciones S.A., 2020)
Background: chronic liver disease (CLD) patients often pres ent thrombocytopenia (TCP) and when severe, it may pre vent them from undergoing necessary invasive procedures due to an increased bleeding risk. The lack of ...
Artículo
CD46 Genetic Variability and HIV-1 Infection Susceptibility
(MDPI, 2021-11-09)
CD46 is the main receptor for complement protein C3 and plays an important role in adaptive immune responses. CD46 genetic variants are associated with susceptibility to several infectious and autoimmune diseases. Additionally, ...
Artículo
Pneumocystis jirovecii transmission from Immunocompetent carriers to infant
(2008)
We report a case of Pneumocystis jirovecii transmission from colonized grandparents to their infant granddaughter. Genotyping of P. jirovecii showed the same genotypes in samples from the infant and her grandparents. These ...
Artículo
Role of blaTEM and OmpC in the piperacillin-tazobactam resistance evolution by E. coli in patients with complicated intra-abdominal infection
(Elsevier, 2023)
Piperacillin-tazobactam resistance (P/T-R) is increasingly reported among Escherichia coli isolates. Although in vitro experiments have suggested that blaTEM gene plays a key role in the P/T-R acquisition, no clinical in ...
Artículo
Concomitant administration of seasonal influenza and COVID-19 mRNA vaccines
(Taylor and Francis Group, 2023)
Current clinical guidelines support the concomitant administration of seasonal influenza vaccines and COVID-19 mRNA boosters vaccine. Whether dual vaccination may impact vaccine immunogenicity due to an interference between ...
Artículo
Hepatopulmonary syndrome: which blood gas analysis criteria and position should we use for diagnosis?
(Aran Ediciones S.A., 2017)
Introduction: Different blood gas criteria have been used in the diagnosis of hepatopulmonary syndrome (HPS). Patients and methods: Arterial blood gases were prospec tively evaluated in 194 cirrhotic candidates for ...