Artículos (Fisiología Médica y Biofísica): Envíos recientes
Mostrando ítems 41-60 de 346
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Peripheral Organ Equivalent Dose Estimation Procedure in Proton Therapy
(Frontiers Research Foundation, 2022)The aim of this work is to present a reproducible methodology for the evaluation of total equivalent doses in organs ...
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Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic parkinsonism model
(Wiley, 2018)Neuroinflammation mediated by chronically activated microglia, largely caused by abnormal accumulation of misfolded ...
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Combined effects of aquaporin-4 and hypoxia produce age-related hydrocephalus
(Elsevier, 2018)Aquaporin-4, present in ependymal cells, in glia limiting and abundantly in pericapillary astrocyte foot pro cesses, and ...
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Succinate dehydrogenase/complex II is critical for metabolic and epigenetic regulation of T cell proliferation and inflammation
(American Association for the Advancement of Science, 2022)Effective T cell-mediated immune responses require the proper allocation of metabolic resources to sustain growth, ...
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Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate
(Nature Publishing Group, 2023)Vaccines against SARS-CoV-2 have been shown to be safe and effective but their protective efficacy against infection in ...
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Mitochondrial Complex I Function Is Essential for Neural Stem/Progenitor Cells Proliferation and Differentiation
(Frontiers Research Foundation, 2019)Neurogenesis in developing and adult mammalian brain is a tightly regulated process that relies on neural stem cell (NSC) ...
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Oxygen regulation of breathing is abolished in mitochondrial complex III-deficient arterial chemoreceptors
(National Academy of Sciences, 2022)Acute oxygen (O2) sensing is essential for adaptation of organisms to hypoxic environments or medical conditions with ...
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Impact of COVID-19 on liver disease: From the experimental to the clinic perspective.
(Baishideng Publishing Group Inc, 2021)Coronavirus disease 2019 (COVID-19) has caused a global pandemic unprecedented in over a century. Although severe acute ...
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Sushi domain-containing protein 4 controls synaptic plasticity and motor learning
(2021)Fine control of protein stoichiometry at synapses underlies brain function and plasticity. How proteostasis is controlled ...
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Innate Immune Receptors, Key Actors in Cardiovascular Diseases
(Elsevier on behalf of the American College of Cardiology Foundation, 2020)Cardiovascular diseases (CVDs) are the leading cause of death in the industrialized world. Most CVDs are associated with ...
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Cellular adaptation to oxygen deficiency beyond the Nobel award
(Willey, 2020)Understanding the cellular adaptation to oxygen deficiency -hypoxia- has a profound impact on our knowledge of the ...
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SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells
(Nature Portfolio, 2020)Glioblastoma cancer-stem like cells (GSCs) display marked resistance to ionizing radiation (IR), a standard of care for ...
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Molecular mechanisms of acute oxygen sensing by arterial chemoreceptor cells. Role of Hif2α
(Frontiers Research Foundation, 2020)Carotid body glomus cells are multimodal arterial chemoreceptors able to sense and integrate changes in several physical ...
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Association of high microvessel alpha(v)beta(3) and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126
(2016-10-26)Neuroblastoma (NB) is the most common extracranial solid tumor in children. Our previous studies showed that the angiogenic ...
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The RhoB small GTPase in physiology and disease
(2016-10-23)RhoB is a Rho family GTPase that is highly similar to RhoA and RhoC, yet has distinct functions in cells. Its unique ...
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Multiple Holdouts With Stability: Improving the Generalizability of Machine Learning Analyses of Brain–Behavior Relationships
(Elsevier, 2020)BACKGROUND: In 2009, the National Institute of Mental Health launched the Research Domain Criteria, an attempt to move ...
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Conservative and disruptive modes of adolescent change in human brain functional connectivity
(National Academy of Sciences, 2020)Adolescent changes in human brain function are not entirely understood. Here, we used multiecho functional MRI (fMRI) to ...
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Practical Application of Networks in Neurosurgery: Combined 3-Dimensional Printing, Neuronavigation, and Preoperative Surgical Planning
(Elsevier, 2020)BACKGROUND: A plethora of cutting-edge neuroimaging analyses have been developed and published, yet they have not hitherto ...
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Ketotifen is a microglial stabilizer by inhibiting secretory vesicle acidification
(Elsevier, 2023)Aims: Microglia survey the brain environment by sensing alarm signals to provide the first line of defense against injury ...
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Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington's disease model mice
(NATURE PUBLISHING GROUP, 2023)Huntington’s disease (HD) is a progressive, neurodegenerative disease caused by a CAG triplet expansion in huntingtin. ...