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Artículo
Expression Pattern of Aquaporin 1 and Aquaporin 3 in Melanocytic and Nonmelanocytic Skin Tumors
(American journal of clinical pathology, 2019)
Objectives: Study of aquaporin 1 (AQP1) and aquaporin 3 (AQP3) expression to understand its potential role in the pathophysiology of skin cancer. Methods: Analysis of AQP1 and AQP3 expression by immunohistochemistry ...
Artículo
Combined effects of aquaporin-4 and hypoxia produce age-related hydrocephalus
(Elsevier, 2018)
Aquaporin-4, present in ependymal cells, in glia limiting and abundantly in pericapillary astrocyte foot pro cesses, and aquaporin-1, expressed in choroid plexus epithelial cells, play an important role in cerebrospinal fluid ...
Artículo
Role of aquaporins in cell proliferation: What else beyond water permeability?
(Taylor & Francis Open Access, 2016-02-21)
In addition to the extensive data demonstrating the importance of mammalian AQPs for the movement of water and some small solutes across the cell membrane, there is now a growing body of evidence indicating the involvement ...
Artículo
Overexpression of AQP3 Modifies the Cell Cycle and the Proliferation Rate of Mammalian Cells in Culture
(PUBLIC LIBRARY SCIENCE, 2015-09-14)
Abnormal AQP3 overexpression in tumor cells of different origins has been reported and a role for this enhanced AQP3 expression in cell proliferation and tumor processess has been indicated. To further understand the role ...
Artículo
Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound
(Public Library of Science, 2012-05-18)
Aquaporins (AQPs) are membrane channels that conduct water and small solutes such as glycerol and are involved in many physiological functions. Aquaporin-based modulator drugs are predicted to be of broad potential utility ...
Artículo
Functional and transcriptional induction of Aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α
(2011)
Aquaporin-1 (AQP1) is a water channel that is highly expressed in tissues with rapid O2 transport. It has been reported that this protein contributes to gas permeation (CO2, NO and O2) through the plasma membrane. We show ...
Artículo
AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis
(MDPI, 2019-02-24)
Aquaporin 1 (AQP1), expressed in epithelial cells of the choroid plexus, and aquaporin 4 (AQP4) present in ependymal cells and glia limitants have been proposed to play a significant role in cerebrospinal fluid (CSF) ...
Artículo
Long-term immunosuppression for CNS mouse xenotransplantation: Effects on nigrostriatal neurodegeneration and neuroprotective carotid body cell therapy
(Wiley, 2018)
Abstract Background: The use of long-term immunosuppressive treatments on neural trans plantation has been controversial during the last decades. Although nowadays there is a consensus about the necessity of maintaining ...
Tesis Doctoral
Acuaporinas en diversas patologías neurológicas
(2016-06-17)
El agua es un compuesto esencial para la vida. La mayoría de las moléculas (iones, azúcares, proteínas, etc.) que forman parte de los seres vivos se encuentran disueltos en medio acuoso. Para realizar sus funciones, las ...
Artículo
Comparative analysis for the presence of IgG anti-aquaporin-1 in patients with NMO-Spectrum disorders
(MDPI AG, 2016-07-23)
Detection of IgG anti-Aquaporin-4 (AQP4) in serum of patients with Neuromyelitis optica syndrome disorders (NMOSD) has improved diagnosis of these processes and differentiation from Multiple sclerosis (MS). Recent findings ...