Browsing Artículos (Farmacología) by Subject "DNA damage"
Now showing items 1-5 of 5
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Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
(MDPI AG, 2016)Epidemiological studies have found a positive association between coffee consumption and a lower risk of cardiovascular ...
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Effect of DNA repair deficiencies on the cytotoxicity of resveratrol
(2015)Numerous preclinical studies have shown that the naturally-occurring polyphenol resveratrol may produce health-beneficial ...
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Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Previously, we reported that MTH1 inhibitors TH588 and TH1579 selectively induce oxidative damage and kill Ras-expressing ...
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The Cockayne syndrome protein B is involved in the repair of 5-AZA-2′-deoxycytidine-induced DNA lesions
(Impact Journals, 2018)The Cockayne Syndrome Protein B (CSB) plays an essential role in Transcription-Coupled Nucleotide Excision Repair (TC-NER) ...
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Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination
(Elsevier, 2017)Zebularine is a second-generation, highly stable hydrophilic inhibitor of DNA methylation with oral bioavailability that ...