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Artículo
Elaboración y caracterización de una suspensión oleosa de omeprazol para su administración en pediatría
(Editorial Universidad de Granada, 2012)
Objetivo: Desarrollar una suspensión de omeprazol oral destinada a la población pediátrica. Métodos: Para el desarrollo de la formulación se empleó el principio activo en polvo en lugar de pellets, que es lo que habitualmente ...
Artículo
Preparation, characterization and evaluation of the anti-inflammatory activity of epichlorohydrin-β-cyclodextrin/curcumin binary systems embedded in a pluronic® /hyaluronate hydrogel
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Curcumin (Cur) is an anti-inflammatory polyphenol that can be complexed with polymeric cyclodextrin (CD) to improve solubility and bioavailability. The aim of the present work was to prepare a CurCD hydrogel to treat ...
Artículo
Topical Application of Glycolipids from Isochrysis galbana Prevents Epidermal Hyperplasia in Mice
(Multidisciplinary Digital Publishing Institute (MDPI), 2018)
Chronic inflammatory skin diseases such as psoriasis have a significant impact on society. Currently, the major topical treatments have many side effects, making their continued use in patients difficult. Microalgae have ...
Artículo
Biologically Relevant Micellar Nanocarrier Systems for Drug Encapsulation and Functionalization of Metallic Nanoparticles
(MDPI, 2022)
The preparation of new and functional nanostructures has received more attention in the scientific community in the past decade due to their wide application versatility. Among these nanostructures, micelles appear to be ...
Artículo
Synergistic effect of acetazolamide-(2-hydroxy)propyl β-cyclodextrin in timolol liposomes for decreasing and prolonging intraocular pressure levels
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
The purpose of this study was to design, for the first time, a co-loaded liposomal formulation (CLL) for treatment of glaucoma including timolol maleate (TM) in the lipid bilayer and acetazolamide (Acz)-(2-hydroxy)propyl ...
Artículo
Cholesterol levels affect the performance of aunps-decorated thermo-sensitive liposomes as nanocarriers for controlled doxorubicin delivery
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Stimulus-responsive liposomes (L) for triggering drug release to the target site are particularly useful in cancer therapy. This research was focused on the evaluation of the effects of cholesterol levels in the performance ...
Artículo
Didodecyldimethylammonium Bromide Role in Anchoring Gold Nanoparticles onto Liposome Surface for Triggering the Drug Release
(Springer, 2019-08-20)
Liposomes with their capacity to anchor gold nanoparticles (AuNPs) onto their surface are used in the treatment of several pathologies such as cancer. The objective of this work was the optimization of the vesicle composition ...
Artículo
Avances en las formulaciones de los antisépticos
(Universidad de Granada, 2021)
Objetivo: Revisar nuevas formulaciones antisépticas que minimicen los inconvenientes de las formulaciones convencionales y mejoren la efectividad los tratamientos actualmente usados. Metodología: Se ha realizado una ...
Artículo
Association of immunological cell profiles with specific clinical phenotypes of scleroderma disease
(Hindawi Publishing Corporation, 2014)
This study aimed to search the correlation among immunological profiles and clinical phenotypes of scleroderma in well- characterized groups of scleroderma patients, comparing forty-nine scleroderma patients stratified ...
Artículo
Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Systemic lupus erythematosus (SLE) is a chronic immune-inflammatory disease characterized by multiorgan affectation and lowered self-tolerance. Additionally, epigenetic changes have been described as playing a pivotal role ...