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Article
Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs
(Wolters Kluwer Health, 2010)
Oxidative therapy is a relatively new anticancer strategy based on the induction of high levels of oxidative stress, achieved by increasing intracellular reactive oxygen species (ROS) and/or by depleting the ...
Article
Cancer nano-immunotherapy: the novel and promising weapon to fight cancer
(Mdpi Ag, 2024)
Cancer is a complex disease that, despite advances in treatment and the greater understanding of the tumor biology until today, continues to be a prevalent and lethal disease. Chemotherapy, radiotherapy, and surgery are ...
Article
Expression of a neu/c-erbB-2-like product in neuroendocrine cells of mammals
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2000-01-01)
The neulc-erbB-2 oncogen encodes a 185 kDa protein closely homologous to the epidermal growth factor receptor. The protein product (p185) is a glycoprotein with an external domain and an internal domain with tyrosine kinase ...
Article
Mature Cystic Teratoma of the Lung With a Somatic-Like Malignant Component in a Patient With Testicular Germ-Cell Tumor
(Sociedad Española de Neumología y Cirugía Torácica SEPAR, 2018-12)
In urological oncology, the diagnosis of teratoma with a somatic-like malignant component refers to the presence of a malignant neoplasm, e.g. carcinoma or sarcoma, either within a teratoma of the genital tract (usually ...
Article
Decrease in calcitonin and parathyroid hormone mRNA levels and hormone secretion under long-term hypervitaminosis D3 in rats
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2001-04-25)
In calcium homeostasis, vitamin D3 is a potent serum calcium-raising agent which in vivo regulates both calcitonin (CT) and parathyroid hormone (PTH) gene expression. Serum calcium is the major secretagogue for CT, a hormons ...
Article
RING1B recruits EWSR1-FLI1 and cooperates in the remodeling of chromatin necessary for Ewing sarcoma tumorigenesis
(American Association for the Advancement of Science, 2020)
Ewing sarcoma (EwS) is an aggressive tumor that affects adolescents and young adults. EwS is defined by a chromosomal translocation, EWSR1-FLI1 being the most common, that causes genome reprogramming through ...
Article
Silencing of histone deacetylase 6 decreases cellular malignancy and contributes to primary cilium restoration, epithelial-to-mesenchymal transition reversion, and autophagy inhibition in glioblastoma cell lines
(MDPI, 2021)
Glioblastoma multiforme, the most common type of malignant brain tumor as well as the most aggressive one, lacks an effective therapy. Glioblastoma presents overexpression of mesenchymal markers Snail, Slug, and N-Cadherin ...
Article
Postnatal Fate of the Ultimobranchial Remnants in the Rat Thyroid Gland
(Wiley Periodicals, Inc., 2013-07)
The ultimobranchial follicles (UBFs) areconsidered embryonic remnants from the ultimobran-chial body (UBB). They are follicular structures thatvary in size and appearance depending on the age of therat. ...
Article
Promoción de salud en centros de personas mayores ante el coronavirus mediante el uso de títeres
(Ediciones Complutense, 2021)
El confinamiento como medida preventiva ante la COVID19 ha supuesto un alto coste emocional y psicológico a la población en general y especialmente a las personas mayores. Resulta relevante la promoción de factores asociados ...
Article
Influence of Femtosecond Laser Modification on Biomechanical and Biofunctional Behavior of Porous Titanium Substrates
(MDPI, 2022-04)
Bone resorption and inadequate osseointegration are considered the main problems of titanium implants. In this investigation, the texture and surface roughness of porous titanium samples obtained by the space holder technique ...