• Article
  

  Anti-obesogenic effect of lupin-derived protein hydrolysate through modulation of adiposopathy, insulin resistance and gut dysbiosis in a diet-induced obese mouse 

  Ponce España, Eduardo; Cruz Chamorro, Iván; Santos Sánchez, Guillermo; Alvarez-Lopez, Ana Isabel; Fernández-Santos, José María; Pedroche, Justo; Millán-Linares, MC; Bejarano Hernando, Ignacio; Lardone, Patricia Judith; Carrillo Vico, Antonio (Elsevier, 2024)

  The prevalence of obesity is increasingly widespread, resembling a global epidemic. Lifestyle changes, such as consumption ...

• Article
  

  Biological Response of the Peri-Implant Mucosa to Different Definitive Implant Rehabilitation Materials 

  Baus Domínguez, María; Oliva-Ferrusola, Elena; Maza-Solano, Serafín; Ruiz-de-León, Gonzalo; Serrera Figallo, María de los Ángeles; Gutiérrez Pérez, José Luis; Torres-Lagares, Daniel; Macías García, Laura (MDPI, 2024-05-29)

  Background: Sealing the peri-implant tissue is a determining factor for long-term implant survival. In the transmucosal ...

• Article
  

  Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells 

  Villanueva-Paz, Marina; Cordero, Mario D.; Pavón, Ana Delgado; Castejón Vega, Beatriz; Cotán, David; De la Mata, Mario; Oropesa-Ávila, Manuel; Alcocer-Gómez, Elísabet; Muntané Relat, Jordi; Miguel Rodríguez, Manuel de; Sánchez-Alcázar, José Antonio (2016-08-07)

  Systemic treatments for hepatocellular carcinoma (HCC) have been largely unsuccessful. This study investigated the ...

• Article
  

  Effects of polyphenolic maqui ( Aristotelia chilensis ) extract on the inhibition of NLRP3 inflammasome and activation of mast cells in a mouse model of Crohn's disease-like colitis 

  Ortiz Cerda, Tamara Andrea; Argüelles Arias, Federico; Macías García, Laura; Vázquez Román, María Victoria; Tapia, Gladys; Xie, Kangzhe; García-García, María Desirée; Merinero de los Santos, Manuel; García Montes, Josefa María; Alcudia Cruz, Ana; Witting, Paul K.; Miguel Rodríguez, Manuel de (Frontiers Media S.A., 2024-01-12)

  Introduction: Crohn’s disease (CD) involves activation of mast cells (MC) and NFкB in parallel with the PPAR-a/NLRP3 ...

• Article
  

  C-cell differentiation in the wall of an aberrant ultimobranchial sinus in the thyroid gland of an old rat 

  Vázquez Román, María Victoria; Fernández-Santos, José María; Martín Lacave, Inés María (Wiley, 2022)

  Background In mammals, the thyroid gland possesses two types of endocrine cells, follicular cells and C cells, which ...

• Article
  

  Cancer nano-immunotherapy: the novel and promising weapon to fight cancer 

  García-Domínguez, Daniel J.; López Enriquez, Soledad; Alba Jiménez, Gonzalo; Garnacho Montero, Carmen; Jiménez Cortegana, Carlos; Flores-Campos, Rocío; Cruz Merino, Luis de la; Hajji, Nabil; Sánchez Margalet, Víctor; Hontecillas-Prieto, Lourdes (Mdpi Ag, 2024)

  Cancer is a complex disease that, despite advances in treatment and the greater understanding of the tumor biology until ...

• Article
  

  Behaviour of the Peri-Implant Soft Tissue with Different Rehabilitation Materials on Implants 

  Baus Domínguez, María; Maza Solano, Serafín; Vazquez-Pachon, Celia; Flores-Cerero, Marta; Torres Lagares, Daniel; Serrera Figallo, María de los Ángeles; Macías García, Laura (MDPI, 2023-08)

  Background: Mucointegration seems to gain interest when talking about success in the maintenance of dental implants. As ...

• Article
  

  VE-Cadherin modulates β-catenin/TCF-4 to enhance vasculogenic mimicry 

  Delgado-Bellido, Daniel; Zamudio-Martínez, Esteban; Fernández-Cortés, Mónica; Herrera-Campos, Ana Belén; Olmedo Pelayo, Joaquín; Jordán Pérez, Carmen; Álava Casado, Enrique de; Oliver, F. J. (Nature Publishing Group, 2023)

  Vasculogenic Mimicry (VM) refers to the capacity to form a blood network from aggressive cancer cells in an independent ...

• Article
  

  Qué es la epigenética 

  Rivero Canalejo, Sabrina (Universidad de Sevilla, 2018)

  El término epigenética hace referencia al estudio de los mecanismos por medio de los cuales el genotipo, o la información ...

• Article
  

  Cost-effectiveness analysis of molecular diagnosis by next-generation sequencing versus sequential single testing in metastatic non-small cell lung cancer patients from a south Spanish hospital perspective 

  Álava Casado, Enrique de; Pareja, María Jesús; Carcedo, David; Arrabal, Natalia; García, José-Francisco; Bernabé-Caro, Reyes (Taylor and Francis LTD, 2022)

  Background: To assess the cost-effectiveness of using next-generation sequencing (NGS) compared to sequential single-testing ...

• Article
  

  Collision tumour involving a rectal gastrointestinal stromal tumour with invasion of the prostate and a prostatic adenocarcinoma 

  Macías García, Laura; Hoz-Herazo, Haydee de la; Robles Frías, Antonio; Pareja Megía, María Jesús; López-Garrido, Juan; López, José Ignacio (BMC, 2012-10-30)

  Background: Gastrointestinal stromal tumours (GISTs) are the most common primary mesenchymal neoplasia in the ...

• Article
  

  Infiltration of abdominal striae distensae by Hodgkin's lymphoma 

  Macías García, Laura; Vallejo Benítez, Ana; Márquez-García, Ana; Marcos Domínguez, Ángel José; Ríos Martín, Juan José (Wiley, 2018-10)

  Cutaneous Hodgkin’s lymphoma (HL) is generally secondary to dissemination from a nodal HL; it tends to occur late in ...

• Article
  

  Mature Cystic Teratoma of the Lung With a Somatic-Like Malignant Component in a Patient With Testicular Germ-Cell Tumor 

  Vallejo Benítez, Ana; Rodríguez-Zarco, Enrique; Pereira Gallardo, Sofía; Macías García, Laura (Sociedad Española de Neumología y Cirugía Torácica SEPAR, 2018-12)

  In urological oncology, the diagnosis of teratoma with a somatic-like malignant component refers to the presence of a ...

• Article
  

  Postnatal Fate of the Ultimobranchial Remnants in the Rat Thyroid Gland 

  Vázquez Román, María Victoria; Utrilla Alcolea, José Carmelo; Fernández-Santos, José María; Conde Amiano, Esperanza; Bernabé-Caro, Reyes; Sampedro, Consuelo; Martín Lacave, Inés María (Wiley Periodicals, Inc., 2013-07)

  The ultimobranchial follicles (UBFs) areconsidered embryonic remnants from the ultimobran-chial body (UBB). ...

• Article
  

  Immunohistochemical profiling of the ultimobranchial remnants in the rat postnatal thyroid gland 

  Vázquez Román, María Victoria; Utrilla Alcolea, José Carmelo; Fernández-Santos, José María; Martín Lacave, Inés María (Wiley Periodicals, Inc., 2017-05-02)

  Ultimobranchial (UB) remnants are a constant presence in the thyroid throughout rat postnatal life; however, the difficulty ...

• Article
  

  Primary Cilium in the Human Thyrocyte: Changes in Frequency and Length in Relation to the Functional Pathology of the Thyroid Gland 

  Fernández-Santos, José María; Utrilla Alcolea, José Carmelo; Vázquez Román, María Victoria; Villar Rodríguez, José Luis; Gutiérrez-Avilés, Lorenzo; Martín Lacave, Inés María (Mary Ann Liebert, Inc. Publishers, 2019-04)

  Background: Primary cilia (PC) are conserved structures in the adult thyroid gland of different mammals. We have recently ...

• Article
  

  Rac1-PAK1 regulation of Rab11 cycling promotes junction destabilization 

  Erasmus, Jennifer C.; Smolarczyk, Kasia; Brezovjakova, Helena; Mohd-Naim, Noor F.; Lozano Pérez, Encarnación; Matter, Karl; Braga, Vania M. M. (Rockefeller University Press, 2021)

  Rac1 GTPase is hyperactivated in tumors and contributes to malignancy. Rac1 disruption of junctions requires its effector ...

• Article
  

  From precision medicine to imprecision medicine through limited diagnostic ability to detect low allelic frequency mutations 

  Serrano, María José; Expósito Hernández, José; Guerrero, Rosa; López Hidalgo, Javier; Aguilar, Mariano; Lorente, José Antonio; Álava Casado, Enrique de; Garrido Navas, María del Carmen (2020)

  Routine molecular testing in NSCLC is currently moving beyond the classical EGFR mutational analysis and the evolving ...

• Article
  

  Estudio de biocompatibilidad y osteointegración de nuevos materiales protésicos 

  Giner García, Mercedes; Santana, L.; Vázquez Gámez, María de los Ángeles; Colmenero, M.; Olmo, F. J.; Chicardi Augusto, Ernesto; Torres Hernández, Yadir; Montoya García, María José (Ibáñez & Plaza, 2020)

  Objetivos Los implantes óseos son utilizados cada vez con mayor frecuencia en la práctica clínica y, entre los materiales, ...

• Article
  

  Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma 

  Gerke, Julia S.; Orth, Martin F.; Tolkach, Yuri; Romero Pérez, Laura; Wehweck, Fabienne S.; Stein, Stefanie; Grünewald, Thomas G. P. (Wiley, 2020)

  In prostate adenocarcinoma (PCa), distinction between indolent and aggressive disease is challenging. Around 50% of PCa ...

View more