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Artículo
Acute oxidant damage promoted on cancer cells by amitriptyline in comparison with some common chemotherapeutic drugs
(Wolters Kluwer Health, 2010)
Oxidative therapy is a relatively new anticancer strategy based on the induction of high levels of oxidative stress, achieved by increasing intracellular reactive oxygen species (ROS) and/or by depleting the ...
Artículo
Amitriptyline down-regulates coenzyme Q10 biosynthesis in lung cancer cells
(Elsevier, 2017)
Amitriptyline, a tricyclic antidepressant, has been proposed as an antitumoral drug in oxidative therapy. Its pro-apoptotic effects, mediated by high reactive oxygen species generation, have been already described. In ...
Artículo
Fibroblasts Collagen Production and Histological Alterations in Hereditary Gingival Fibromatosis
(MDPI, 2019)
Hereditary gingival fibromatosis is a disorder for which the etiology remains unknown. We aimed to evaluate the fibroblasts and histological alterations to give new clues. A father and a daughter of a family showing gingival ...
Artículo
Native Chilean Berries Preservation and In Vitro Studies of a Polyphenol Highly Antioxidant Extract from Maqui as a Potential Agent against Inflammatory Diseases
(MDPI, 2021-05)
The best conservation method for native Chilean berries has been investigated in combination with an implemented large-scale extract of maqui berry, rich in total polyphenols and anthocyanin to be tested in intestinal ...
Artículo
Oxidative Stress Correlates with Headache Symptoms in Fibromyalgia: Coenzyme Q10 Effect on Clinical Improvement
(Public Library of Science, 2012)
Background: Fibromyalgia (FM) is a chronic pain syndrome with unknown etiology and a wide spectrum of symptoms such as allodynia, debilitating fatigue, joint stiffness and migraine. Recent studies have shown some evidences ...