Artículos (Bioquímica y Biología Molecular): Envíos recientes
Mostrando ítems 81-100 de 224
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Biomethane production improvement by enzymatic pre-treatments and enhancers of sewage sludge anaerobic digestion
(Elsevier, 2019)Enzymatic hydrolysis is recognised as an effective pre-treatment for increasing biodegradability of sludge. In this work, ...
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VCAM-1 targeted magnetic resonance imaging enables detection of brain micrometastases from different primary tumours
(American Association for Cancer Research, 2019)Purpose: A major issue for the effective treatment of brain metastasis is the late stage of diagnosis with existing ...
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Neuroinflammation in Alzheimer's Disease
(Elsevier, 2015)Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the neuronal compartment but ...
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Adverse health effects in women farmers indirectly exposed to pesticides
(MDPI, 2021-05-31)Farmers are among the most vulnerable populations because of the exposure to low levels of pesticides. Acetylcholinesterase ...
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Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1
(Springer, 2021)Genetic Alzheimer’s disease (AD) risk factors associate with reduced defensive amyloid β plaque-associated microglia (AβAM), ...
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Impact of Pesticide Exposure among Rural and Urban Female Population. An Overview
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Pesticides are substances that have become widely used in agriculture and the human exposure to these substances may cause ...
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APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer’s disease pathology and brain diseases
(Springer Nature, 2022)ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human polymorphisms, apoE2, apoE3, and ...
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Impairment of mineralocorticoid receptor (MR)-dependent biological response by oxidative stress and aging
(American Society for Biochemistry and Molecular Biology, 2002)Acute and chronic treatments of mice with the gluta- thione-depleting agent, L-buthionine-(SR)-sulfoximine (BSO), impaired ...
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Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus
(Springer, 2012)Dystrophic neurites associated with amyloid plaques precede neuronal death and manifest early in Alzheimer’s disease ...
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A Double-Blind, RCT Testing Beneficial Modulation of BDNF in Middle-Aged, Life Style-Stressed Subjects: A Clue to Brain Protection?
(JCDR, 2014)Introduction: The aim of this prospective study was to see whether LD-1227, a quality-controlled marine nutraceuticals shown ...
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PGC-1α controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity. (Erratum) Aging, 2015; 7(9): 629‐647.
(Impact Journals, 2016)In this article, the additional author Aine Brigette Henley is added to this manuscript: http://www.impactaging.com/papers/v7/n9/pdf/100790.pdf.
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Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration
(Springer Nature, 2022)The advent of high-throughput single-cell transcriptomic analysis of microglia has revealed different phenotypes that are ...
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Galectin-3 Deletion Reduces LPS and Acute Colitis-Induced Pro-Inflammatory Microglial Activation in the Ventral Mesencephalon
(Frontiers Media, 2021)Parkinson’s disease is a highly prevalent neurological disorder for which there is currently no cure. Therefore, the ...
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Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis
(Frontiers Media, 2021)Alzheimer’s disease (AD) is a devastating neurodegenerative disorder characterized by initial memory impairments that ...
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Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease
(Wiley, 2018)Reactive astrogliosis, a complex process characterized by cell hypertrophy and upregulation ofcomponents of intermediate ...
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Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner
(BMC, 2022)Background The risk of developing Alzheimer’s disease (AD) is modulated by genetic and environmental factors. Early-life ...
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Natural Extracts Abolished Lipid Accumulation in Cells Harbouring non-favourable PNPLA3 genotype
(Elsevier, 2018)Background & aims. G-allele of PNPLA3 (rs738409) favours triglycerides accumulation and steatosis. In this study, we ...
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Use of human pluripotent stem cell-derived cells for neurodegenerative disease modeling and drug screening platform
(Future Science Group, 2019)Most neurodegenerative diseases are characterized by a complex and mostly still unresolved pathology. This fact, together ...
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Galectin‑3, a novel endogenous TREM2 ligand, detrimentally regulates infammatory response in Alzheimer’s disease
(Springer, 2019)Alzheimer’s disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of ...
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Distinct disease-sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients
(Wiley Open Access, 2019)Neuronal loss is the best neuropathological substrate that correlates with cortical atrophy and dementia in Alzheimer’s ...