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Artículo
Treatment with mesenchymal stem cells in an animal model of parkinson´s disease
(Federation of Anti-Aging Medicine Societies, 2015)
Artículo
Immunolocalization of Substance P and NK-1 Receptor in ADIPOSE Stem Cells
(Wiley-Blackwell, 2017)
Substance P (SP) is a neuropeptide belonging to the thachykinin peptide family. SP, after binding to its receptor, the neurokinin 1 receptor (NK1R), controls several transcription factors such as NF-κB, hypoxia inducible ...
Artículo
The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma
(Hindawi, 2022)
Background. Glioblastoma or glioma is the most common malignant brain tumor. Patients have a prognosis of approximately 15 months, despite the current aggressive treatment. Neurokinin-1 receptor (NK-1R) occurs naturally ...
Artículo
Irisin enhances longevity by boosting SIRT1, AMPK, autophagy and telomerase
(Cambridge University Press, 2022)
Ageing is characterised by the accumulation of molecular and cellular damage through time, leading to a decline in physical and mental abilities. Currently, society has experienced a rapid increase in life expectancy, which ...
Artículo
Aging and Oxidative Stress Decrease Pineal Elongation Factor 2: In Vivo Protective Effect of Melatonin in Young Rats Treated With Cumene Hydroperoxide
(Wiley-Blackwell, 2017)
We studied the alterations of Elongation Factor 2 (eEF2) in the pineal gland of aged rats as well as the possible protective role of exogenous melatonin on these changes in young rats treated with cumene hydroperoxide (CH), ...
Artículo
Chronic Stress Alters the Expression Levels of Longevity-related Genes in the Rat Hippocampus
(Elsevier, 2016)
The molecular mechanisms underlying the negative effects of psychological stress on cellular stress during aging and neurodegenerative diseases are poorly understood. The main objective of this study was to test the effect ...
Artículo
Cell Tracking, Survival, and Differentiation Capacity of Adipose-Derived Stem Cells After Engraftment in Rat Tissue
(Wiley-Blackwell, 2018)
Adipose tissue is an important source of adipose derived stem cells (ADSCs). These cells have the potential of being used for certain therapies, in which the main objective is to recover the function of a tissue/organ ...