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Mostrando ítems 101-110 de 223
Artículo
Glutaredoxins are essential for stress adaptation in the cyanobacterium Synechocystis sp. PCC 6803
(Frontiers media, 2013)
Glutaredoxins are small redox proteins able to reduce disulfides and mixed disulfides between GSH and proteins. Synechocystis sp. PCC 6803 contains three genes coding for glutaredoxins: ssr2061 (grxA) and slr1562 (grxB) ...
Artículo
Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration
(Nature, 2017)
Traumatic brain injury (TBI) is currently a major cause of morbidity and poor quality of life in Western society, with an estimate of 2.5 million people affected per year in Europe, indicating the need for advances in TBI ...
Artículo
Microglial subtypes: diversity within the microglial community
(EMBO Press, 2019)
Microglia are brain-resident macrophages forming the first active immune barrier in the central nervous system. They fulfill multiple functions across development and adulthood and under disease conditions. Current ...
Artículo
Conversion of Whey into Value-Added Products through Fermentation and Membrane Fractionation
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
The cheese whey (95% composed of water) is an effluent produced in the cheese industry, of which more than 1.5 million tons are generated in Spain, constituting a serious environmental problem. The process starts with a ...
Artículo
Microglia: Agents of the CNS Pro-Inflammatory Response
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative diseases. Though the research of microglia spans over a century, the last two decades have ...
Artículo
NADPH-thioredoxin reductase c mediates the response to oxidative stress and thermotolerance in the cyanobacterium anabaena sp. pcc7120
(Frontiers Media S.A., 2016)
NADPH-thioredoxin reductase C (NTRC) is a bimodular enzyme composed of an NADPH-thioredoxin reductase and a thiioredoxin domain extension in the same protein. In plants, NTRC has been described to be involved in the ...
Artículo
Treatment with trkC agonist antibodies delays disease progression in neuromuscular degeneration (nmd) mice
(OXFORD UNIV PRESS, 2005)
Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a fatal autosomal recessive disorder seen in infants. It is characterized by lower motor neuron degeneration, progressive muscle paralysis and respiratory ...
Artículo
How the Local Geometry of the Cu-Binding Site Determines the Thermal Stability of Blue Copper Proteins
(Elsevier, 2011-01)
Identifying the factors that govern the thermal resistance of cupredoxins is essential for understanding their folding and stability, and for improving our ability to design highly stable enzymes with potential biotechnological ...
Artículo
Polyurethane Foam Residue Biodegradation through the Tenebrio molitor Digestive Tract: Microbial Communities and Enzymatic Activity
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Polyurethane (PU) is a widely used polymer with a highly complex recycling process due to its chemical structure. Eliminating polyurethane is limited to incineration or accumulation in landfills. Biodegradation by enzymes ...
Artículo
Analysis of ceftriaxone and ceftazidime distribution in cerebrospinal fluid of and cerebral extracellular space in awake rats by in vivo microdialysis
(American Society for Microbiology, 1995)
In vivo microdialysis was used to estimate the extracellular concentrations of ceftazidime and ceftriaxone, two expanded-spectrum cephalosporins commonly used in the treatment of bacterial meningitis, in two brain regions ...