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Artículo
Inflammatory bowel disease induces pathologicalα-synucleinaggregation in the human gut and brain
(Wiley, 2024-01-16)
Aims According to Braak's hypothesis, it is plausible that Parkinson's disease (PD) originates in the enteric nervous system (ENS) and spreads to the brain through the vagus nerve. In this work, we studied whether ...
Artículo
Microglial Caspase-3 is essential for modulating hippocampal neurogenesis.
(Elsevier, 2023)
Adult hippocampal neurogenesis (AHN) is a process involved in numerous neurodegenerative diseases. Many researchers have described microglia as a key component in regulating the formation and migration of new neurons ...
Artículo
Inflammatory Animal Models of Parkinson's Disease
(IOS Press, 2022)
Accumulating evidence suggests that microglia and peripheral immune cells may play determinant roles in the pathogenesis of Parkinson's disease (PD). Consequently, there is a need to take advantage of immune-related models ...
Artículo
Chronic Stress Alters the Expression Levels of Longevity-related Genes in the Rat Hippocampus
(Elsevier, 2016)
The molecular mechanisms underlying the negative effects of psychological stress on cellular stress during aging and neurodegenerative diseases are poorly understood. The main objective of this study was to test the effect ...