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Burguillos García, Miguel Ángel (16)
Venero Recio, José Luis (13)Espinosa Oliva, Ana María (6)Kavanagh, Edel T. (6)Joseph, Bertrand (5)Carrillo Jiménez, Alejandro (4)García Revilla, Juan (4)Martínez de Pablos, Rocío (4)Boza Serrano, Antonio (3)Deierborg, Tomas (3)... View MoreSubjectmicroglia (4)Microglia (3)neuroinflammation (2)Parkinson’s disease (2)TREM2 (2)Alzheimer’s disease (1)astrocytes (1)Bcl-2 (1)Bcl-xL (1)Caspace-8 (1)... View MoreDate Issued2019 (4)2015 (3)2014 (2)2020 (2)2022 (2)2016 (1)2017 (1)2018 (1)Funding agencyJunta de Andalucía (1)Ministerio de Economía y Competitividad (MINECO). España (1)Ministerio de Educación, Cultura y Deporte (MECD). España (1)Universidad de Sevilla US-1265062, US-1264806 (1)
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Article
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Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation 

Carrillo Jiménez, Alejandro; Puigdellívol, Mar; Vilalta, Anna; Venero Recio, José Luis; Brown, Charles Guy; Burguillos García, Miguel Ángel (Frontiers Media, 2018)
Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, including Alzheimer’s disease (AD). The use of primary microglial cell cultures has proved to be a ...
Article
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Magnetofection as a new tool to study microglia biology 

Venero Recio, José Luis; Burguillos García, Miguel Ángel (Medknow Publications, 2019)
Article
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Brainiac Caspases: Beyond the Wall of Apoptosis 

Espinosa Oliva, Ana María; García Revilla, Juan; Alonso Bellido, Isabel María; Burguillos García, Miguel Ángel (Frontiers Media, 2019)
For the last two decades, caspases, a family of cysteine-aspartic proteases, have evolved from being considered solely as regulators of apoptosis or inflammation to having a wider range of functions. In this mini review, ...
Article
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TET2, an ambiguous player in inflammation 

Espinosa Oliva, Ana María; Burguillos García, Miguel Ángel (2020)
Article
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Microglia: Agents of the CNS Pro-Inflammatory Response 

Rodríguez Gómez, José Antonio; Kavanagh, Edel T.; Engskog-Vlachos, Pinelopi; Engskog, Mikael; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Joseph, Bertrand; Hajji, Nabil; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative diseases. Though the research of microglia spans over a century, the last two decades have ...
Article
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TET2 Regulates the Neuroinflammatory Response in Microglia 

Carrillo Jiménez, Alejandro; Ruiz Laza, Rocío; García Domínguez, Irene; García Revilla, Juan; Espinosa Oliva, Ana María; Venero Recio, José Luis; Burguillos García, Miguel Ángel; Tayara, Khadija (Elsevier, 2019)
Epigenomic mechanisms regulate distinct aspects of the inflammatory response in immune cells. Despite the central role for microglia in neuroinflammation and neurodegeneration, little is known about their epigenomic ...
Article
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Reformulating Pro-Oxidant Microglia in Neurodegeneration 

García Revilla, Juan; Alonso Bellido, Isabel María; Burguillos García, Miguel Ángel; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Ruiz Laza, Rocío; Cruz Hernández, Luis; García Domínguez, Irene; Roca Ceballos, María Angustias; Santiago Pavón, Martiniano; Rodríguez Gómez, José Antonio; Sarmiento Soto, Manuel; Martínez de Pablos, Rocío; Venero Recio, José Luis (MDPI, 2019)
In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent genome-wide transcriptomic analyses of microglial cells under different disease conditions have uncovered ...
Article
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Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia 

Kavanagh, Edel T.; Rodhe, Johanna; Burguillos García, Miguel Ángel; Venero Recio, José Luis; Joseph, Bertrand (Nature Publishing Group, 2014)
The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity are typical features of neurodegenerative diseases, for example, Alzheimer's and Parkinson's diseases. ...
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Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation 

Burguillos García, Miguel Ángel; Svensson, Martina; Schulte, Tim; Boza Serrano, Antonio; García Quintanilla, Alberto; Kavanagh, Edel T.; Santiago Pavón, Martiniano; Viceconte, Nikenza; Oliva Martín, María José; Osman, Ahmed Mohamed; Salomonsson, Emma; Amar, Lahouari; Persson, Annette; Blomgren, Klas; Achour, Adnane; Englund, Elisabet; Leffler, Hakon; Venero Recio, José Luis; Joseph, Bertrand; Deierborg, Tomas (2015)
Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory diseases. Although the role of toll-like receptor 4 (TLR4) in microglia’s inflammatory response ...
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Deletion of caspase-8 in mouse myeloid cells blocks microglia pro-inflammatory activation and confers protection in MPTP neurodegeneration model 

Kavanagh, Edel T.; Burguillos García, Miguel Ángel; Carrillo Jiménez, Alejandro; Oliva Martín, María José; Santiago Pavón, Martiniano; Rodhe, Johanna; Joseph, Bertrand; Venero Recio, José Luis (Impact Journals, LLC, 2015)
Increasing evidence involves sustained pro-inflammatory microglia activation in the pathogenesis of different neurodegenerative diseases, particularly Parkinson's disease (PD). We recently uncovered a completely novel and ...
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