Listar Artículos (Bioquímica y Biología Molecular) por agencia financiadora 

Listar Artículos (Bioquímica y Biología Molecular) por agencia financiadora "Instituto de Salud Carlos III"

Mostrando ítems 1-20 de 24

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      A metagenome-wide association study of HIV disease progression in HIV controllers 

      Real, Luis Miguel; Sáez, María E.; Corma Gómez, Anaïs; González Pérez, Antonio; Thorball, Christian; Ruiz Laza, Rocío; Jiménez León, María Reyes; González-Serna Martín, Manuel Alejandro; Bachiller, Sara; Ruiz Mateos, Ezequiel (Elsevier, 2023)
      Some HIV controllers experience immunologic progression with CD4+ T cell decline. We aimed to identify genetic factors ...
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      Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus 

      Sánchez Varo, Raquel María; Trujillo Estrada, Laura Isabel; Sánchez Mejías, Elisabeth; Torres Canalejo, Manuel; Baglietto Vargas, David; Moreno González, Inés; Jiménez Muñoz, Sebastián; Ruano Caballero, Diego; Vizuete Chacón, María Luisa; Vitorica Ferrández, Francisco Javier; Gutiérrez Pérez, Antonia (Springer, 2012)
      Dystrophic neurites associated with amyloid plaques precede neuronal death and manifest early in Alzheimer’s disease ...
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      Actin Polymerization Defects Induce Mitochondrial Dysfunction in Cellular Models of Nemaline Myopathies 

      Piñero Pérez, Rocío; López Cabrera, Alejandra; Álvarez Córdoba, Mónica; Cilleros Holgado, Paula; Talaverón Rey, Marta; Suárez Carrillo, Alejandra; Munuera Cabeza, Manuel; Gómez Fernández, David; Reche López, Diana; Romero González, Ana Belén; Romero Domínguez, José Manuel; Martínez de Pablos, Rocío; Sánchez Alcázar, José Antonio (Multidisciplinary Digital Publishing Institute (MDPI), 2023-12)
      Nemaline myopathy (NM) is one of the most common forms of congenital myopathy and it is identified by the presence of ...
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      AICAR Stimulates the Pluripotency Transcriptional Complex in Embryonic Stem Cells Mediated by PI3K, GSK3β, and β-Catenin 

      Alba Jiménez, Gonzalo; Martínez, Raquel; Postigo Corrales, Fátima; López Enríquez, Soledad; Santa-María Pérez, Consuelo; Jiménez Carrasco, Juan; Cahuana Macedo, Gladys Margot; Soria Escoms, Bernat; Bedoya Bergua, Francisco Javier; Tejedo Huamán, Juan Rigoberto (American Chemical Society, 2020)
      Pluripotent stem cells maintain the property of self-renewal and differentiate into all cell types under clear environments. ...
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      Amyloid-β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease 

      Sánchez Mico, María; Jiménez Muñoz, Sebastián; Gómez Arboledas, Ángela; Muñoz Castro, Clara; Romero Molina, Carmen; Navarro Garrido, Victoria; Vizuete Chacón, María Luisa; Vitorica Ferrández, Francisco Javier (Wiley, 2020)
      Reactive astrocytes and dystrophic neurites, most aberrant presynaptic elements, are found surrounding amyloid-β plaques ...
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      Distinct disease-sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patients 

      Sánchez Mejías, Elisabeth; Núñez Díaz, Cristina; Sánchez Varo, Raquel María; Gómez Arboledas, Ángela; García León, Juan Antonio; Fernández Valenzuela, Juan José; Vitorica Ferrández, Francisco Javier; Gutiérrez Pérez, Antonia (Wiley Open Access, 2019)
      Neuronal loss is the best neuropathological substrate that correlates with cortical atrophy and dementia in Alzheimer’s ...
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      Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s disease 

      Baglietto Vargas, David; Sánchez Mejías, Elisabeth; Navarro Garrido, Victoria; Jiménez Muñoz, Sebastián; Trujillo Estrada, Laura Isabel; Gómez Arboledas, Ángela; Sánchez Mico, María; Sánchez Varo, Raquel María; Vizuete Chacón, María Luisa; Dávila Cansino, José Carlos; García Verdugo, José Manuel; Vitorica Ferrández, Francisco Javier; Gutiérrez Pérez, Antonia (Nature Research (part of Springer Nature), 2017)
      Alzheimer’s disease is a major neurodegenerative disorder that leads to severe cognitive deficits in the elderly population. ...
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      Galectin-3 is elevated in CSF and is associated with A beta deposits and tau aggregates in brain tissue in Alzheimer's disease 

      Boza Serrano, Antonio; Vrillon, Agathe; Minta, Karolina; Paulus, Agnes; Camprubí Ferrer, Lluís; García, Megg; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Deierborg, Tomas (Springer, 2022)
      Galectin-3 (Gal-3) is a beta-galactosidase binding protein involved in microglial activation in the central nervous ...
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      Galectin-3 is upregulated in frontotemporal dementia patients with subtype specificity 

      Borrego Écija, Sergi; Pérez Millan, Agnès; Antonell, Anna; Fort Aznar, Laura; Kaya Tilki, Elif; León Halcón, Alberto; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Boza Serrano, Antonio (Wiley, 2023-11)
      INTRODUCTION Neuroinflammation is a major contributor to the progression of frontotemporal dementia (FTD). Galectin-3 ...
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      Galectin‑3, a novel endogenous TREM2 ligand, detrimentally regulates infammatory response in Alzheimer’s disease 

      Boza Serrano, Antonio; Ruíz Laza, Rocio; Sánchez Varo, Raquel María; García Revilla, Juan; Yang, Yiyi; Jiménez Ferrer, Itzia; Jiménez Muñoz, Sebastián; Roca Ceballos, María Angustias; Navarro Garrido, Victoria; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Deierborg, Tomas (Springer, 2019)
      Alzheimer’s disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of ...
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      Genetic Rescue of Mitochondrial and Skeletal Muscle Impairment in an Induced Pluripotent Stem Cells Model of Coenzyme Q10 Deficiency 

      Romero Moya, Damià; Santos Ocaña, Carlos; Castaño, Julio; Garrabou, Gloria; Rodríguez Gómez, José Antonio; Ruiz Bonilla, Vanesa; Bueno, Clara; González Rodríguez, Patricia; Giorgetti, Alessandra; Perdiguero, Eusebio; Prieto, Cristina; Moren Núñez, Constanza; Fernández Ayala, Daniel J.; Victoria Cascajo, María; Velasco, Iván; Canals, Josep María; Montero, Raquel; Yubero, Delia; Jou, Cristina; López Barneo, José; Cardellac, Francesc; Muñoz Cánoves, Pura; Artuch, Rafael; Navas, Plácido; Menéndez, Pablo (Wiley-Blackwell, 2017-07)
      Coenzyme Q10 (CoQ10) plays a crucial role in mitochondria as an electron carrier within the mitochondrial respiratory chain ...
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      Human Pluripotent Stem Cell-Derived Neural Cellsas a Relevant Platform for Drug Screening inAlzheimer’s Disease 

      García León, Juan Antonio; Cáceres Palomo, Laura; Sánchez Mejías, Elisabeth; Mejías Ortega, Marina; Núñez Díaz, Cristina; Fernández Valenzuela, Juan José; Sánchez Varo, Raquel María; Dávila Cansino, José Carlos; Vitorica Ferrández, Francisco Javier; Gutiérrez, Antonia (MDPI, 2020)
      Extracellular amyloid-beta deposition and intraneuronal Tau-laden neurofibrillary tanglesare prime features of Alzheimer’s ...
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      Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1 

      March Diaz, Rosana; Lara Ureña, Nieves; Romero Molina, Carmen; Heras Garvin, Antonio; Ortega de San Luis, Clara; Alvarez Vergara, Maria I.; Navarro Garrido, Victoria; Sánchez Mico, María Victoria; Vizuete Chacón, María Luisa; López Barneo, José; Vitorica Ferrández, Francisco Javier; Pascual, Alberto (Springer, 2021)
      Genetic Alzheimer’s disease (AD) risk factors associate with reduced defensive amyloid β plaque-associated microglia (AβAM), ...
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      In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer’s disease pathology 

      Trujillo Estrada, Laura Isabel; Jiménez Muñoz, Sebastián; Castro, Vanessa de; Torres Canalejo, Manuel; Baglietto Vargas, David; Moreno González, Inés; Navarro Garrido, Victoria; Sánchez Varo, Raquel María; Sánchez Mejías, Elisabeth; Dávila Cansino, José Carlos; Vizuete Chacón, María Luisa; Gutiérrez Pérez, Antonia; Vitorica Ferrández, Francisco Javier (BioMed Central, 2013)
      Background: Alzheimer’s disease (AD) is characterized by the abnormal accumulation of extracellular beta-amyloid (Abeta) ...
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      Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells 

      García Bonilla, María; García-Martín, María Luisa; Ojeda Pérez, Betsaida; Muñoz Hernández, Mª Carmen; Vitorica Ferrández, Francisco Javier; Jiménez Muñoz, Sebastián; Cifuentes, Manuel; Santos Ruíz, Leonor; Shumilov, Kirill; Claros, Silvia; Páez González, Patricia; Jiménez, Antonio J. (BMC, 2020)
      BACKGROUND: In obstructive congenital hydrocephalus, cerebrospinal fluid accumulation is associated with high intracranial ...
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      Phages in Food Industry Biocontrol and Bioremediation 

      Cristobal Cueto, Pablo; García Quintanilla, Alberto; Esteban, Jaime; García Quintanilla, Meritxell de Jesús (MDPI, 2021)
      Bacteriophages are ubiquitous in nature and their use is a current promising alternative in biological control. Multidrug ...
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      Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease 

      Gómez Arboledas, Ángela; Dávila Cansino, José Carlos; Sánchez Mejías, Elisabeth; Navarro Garrido, Victoria; Núñez Díaz, Cristina; Sánchez Varo, Raquel María; Sánchez Mico, María; Vizuete Chacón, María Luisa; Vitorica Ferrández, Francisco Javier; Gutiérrez Pérez, Antonia (Wiley, 2018)
      Reactive astrogliosis, a complex process characterized by cell hypertrophy and upregulation ofcomponents of intermediate ...
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      Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis 

      Sánchez Varo, Raquel María; Sánchez Mejías, Elisabeth; Fernández Valenzuela, Juan José; Castro, Vanessa de; Mejías Ortega, Marina; Gómez Arboledas, Ángela; Jiménez, Sebastián; Sánchez Mico, María; Vizuete Chacón, María Luisa; Vitorica Ferrández, Francisco Javier; Gutiérrez, Antonia (Frontiers Media, 2021)
      Alzheimer’s disease (AD) is a devastating neurodegenerative disorder characterized by initial memory impairments that ...
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      Regional difference in inflammatory response to LPS-injection in the brain: Role of microglia cell density 

      Pintado Losa, Cristina; Revilla Torres, María Elisa; Vizuete Chacón, María Luisa; García Cuervo, Luisa; Vitorica Ferrández, Francisco Javier; Ruano Caballero, Diego; Castaño Navarro, Angélica (Elsevier, 2011)
      To elucidate whether density of cells could contribute to the extent of microglial activation, we performed in vitro assays ...
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      Selective deletion of Caspase-3 gene in the dopaminergic system exhibits autistic-like behaviour 

      García Domínguez, Irene; Suárez Pereira, Irene; Santiago Pavón, Martiniano; Pérez Villegas, Eva M.; Bravo, Lidia; López Martín, Carolina; Roca Ceballos, María Angustias; García Revilla, Juan; Espinosa Oliva, Ana María; Rodríguez Gómez, José Antonio; Joseph, Bertrand; Berrocoso, Esther; Armengol, José Ángel; Venero Recio, José Luis; Ruiz Laza, Rocío; Martínez de Pablos, Rocío (Elsevier, 2021-01-10)
      Apoptotic caspases are thought to play critical roles in elimination of excessive and non-functional synapses and removal ...