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Artículo
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Application of a Protein Hydrolysate-Based Biostimulant Obtained from Slaughterhouse Sludge on Pepper Crops
(MDPI, 2023-10-01)
Currently, biostimulants obtained from protein hydrolysates are considered essential agronomic tools to promote sustainable agriculture without the use of chemical fertilizers. This study aimed to investigate the effectiveness ...
Tesis Doctoral
Tesis Doctoral
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La hemoglobina glicosilada (HbA1C) en la intolerancia a la glucosa
(2008-04-22)
La intolerancia a la glucosa representa, junto con la glucemia basal alterada, una etapa intermedia en la historia natural de la diabetes mellitus. Si bien no es considerada una entidad clínica per sé, sí constituye un ...
Artículo
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Hydroxytyrosol and Parkinson’s disease: protective actions against alpha-synuclein toxicity
(Medknow Publications, 2024-07)
Artículo
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Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Alzheimer’s disease (AD) constitutes the most prominent form of dementia among elderly individuals worldwide. Disease modeling using murine transgenic mice was first initiated thanks to the discovery of heritable mutations ...
Artículo
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Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells
(BMC, 2020)
BACKGROUND: In obstructive congenital hydrocephalus, cerebrospinal fluid accumulation is associated with high intracranial pressure and the presence of periventricular edema, ischemia/hypoxia, damage of the white matter, ...
Artículo
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Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: Possible implication in parkinson's disease incidence
(Hindawi Publishing Corporation, 2011)
Inflammatory processes described in Parkinson’s disease (PD) and its animal models appear to be important in the progression of the pathogenesis, or even a triggering factor. Here we review that peripheral inflammation ...
Artículo
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The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior
(Frontiers Media S.A., 2022)
In the last decade, new non-apoptotic roles have been ascribed to apoptotic caspases. This family of proteins plays an important role in the sculpting of the brain in the early stages of development by eliminating excessive ...
Artículo
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The role of Galectin-3 in α-synuclein-induced microglial activation
(BioMed Central, 2014)
Background: Parkinson ’ s disease (PD) is the most prevalent neurodegenerative motor disorder. The neuropathology is characterized by intraneuronal protein aggregates of α -synuclein and progressive degeneration of ...
Artículo
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1–42 b -Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death
(Nature Publishing Group, 2013)
1–42 b -Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death L Manterola 1,12 , M Hernando-Rodr ı ́ guez 2,12 , A Ruiz 3,4 , A Apraiz 5 , O Arrizabalaga 5 , L Vello ́ n 6 , E ...