Browsing Bioquímica y Biología Molecular by Title
Now showing items 1-20 of 304
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Article
1–42 b -Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death
(Nature Publishing Group, 2013)1–42 b -Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death L Manterola 1,12 , M Hernando-Rodr ı ...
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A Double-Blind, RCT Testing Beneficial Modulation of BDNF in Middle-Aged, Life Style-Stressed Subjects: A Clue to Brain Protection?
(JCDR, 2014)Introduction: The aim of this prospective study was to see whether LD-1227, a quality-controlled marine nutraceuticals shown ...
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PhD Thesis
A dual tool. The role of the ripoptosome in phagocytic cell activation and differentiation
(2015-10-19)El término ripoptosoma hace referencia a la plataforma molecular que contiene, entre otras, dos proteínas implicadas en ...
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Article
A high redox potential form of cytochrome c550 in photosystem II from Thermosynechococcus elongatus
(American Society for Biochemistry and Molecular Biology Inc., 2011)Cytochrome c550 (cyt c550) is a component of photosystem II (PSII) from cyanobacteria, red algae, and some other eukaryotic ...
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Article
A lupine (Lupinus angustifolious L.) peptide prevents non-alcoholic fatty liver disease in high-fat-diet-induced obese mice
(Royal Society of Chemistry, 2020)Bioactive peptides are related to the prevention and treatment of many diseases. GPETAFLR is an octapeptide that has been ...
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A metagenome-wide association study of HIV disease progression in HIV controllers
(Elsevier, 2023)Some HIV controllers experience immunologic progression with CD4+ T cell decline. We aimed to identify genetic factors ...
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Article
Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus
(Springer, 2012)Dystrophic neurites associated with amyloid plaques precede neuronal death and manifest early in Alzheimer’s disease ...
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Article
Actin Polymerization Defects Induce Mitochondrial Dysfunction in Cellular Models of Nemaline Myopathies
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-12)Nemaline myopathy (NM) is one of the most common forms of congenital myopathy and it is identified by the presence of ...
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Active zones and the readily releasable pool of synaptic vesicles at the neuromuscular junction of the mouse
(SOC NEUROSCIENCE, 2011-02-09)Synchronous neurotransmitter releaseis a highly regulated processthattakes place at specializations atthe presynapticmembrane ...
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Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo
(Public Library of Science, 2017)Background Recent epidemiological evidence has linked hypoxia with the development of Alzheimer disease (AD). A number ...
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Article
Advantages and Disadvantages of Apoptosis in the Aging Process
(Wiley-Blackwell, 2019)Researchers cannot predict as yet how long a human being can live. Life expectancy has been steadily increasing in the ...
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Article
Adverse health effects in women farmers indirectly exposed to pesticides
(MDPI, 2021-05-31)Farmers are among the most vulnerable populations because of the exposure to low levels of pesticides. Acetylcholinesterase ...
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Article
Age-dependent accumulation of soluble amyloid β (Aβ) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-α (sAPPα) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK- 3β pathway in Alzheimer mouse model
(American Society for Biochemistry and Molecular Biology Inc., 2011)Neurotrophins, activating the PI3K/Akt signaling pathway, control neuronal survival and plasticity. Alterations in NGF, ...
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Aging and Oxidative Stress Decrease Pineal Elongation Factor 2: In Vivo Protective Effect of Melatonin in Young Rats Treated With Cumene Hydroperoxide
(Wiley-Blackwell, 2017)We studied the alterations of Elongation Factor 2 (eEF2) in the pineal gland of aged rats as well as the possible protective ...
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Article
AICAR Stimulates the Pluripotency Transcriptional Complex in Embryonic Stem Cells Mediated by PI3K, GSK3β, and β-Catenin
(American Chemical Society, 2020)Pluripotent stem cells maintain the property of self-renewal and differentiate into all cell types under clear environments. ...
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PhD Thesis
Alteraciones morfofuncionales provocadas en el riñón e hígado de rata tras la administración del pesticida atrazina
(1983-10-01)Los Pesticidas o Plaguicidas han supuesto un gran adelanto en la Agricultura, sin embargo, y ya que su utilización es cada ...
- PhD Thesis
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Article
Altered Intracellular Ca2+ Homeostasis in Nerve Terminals of Severe Spinal Muscular Atrophy Mice
(SOC NEUROSCIENCE, 2010)Low levels of survival motor neuron (SMN) protein result in spinal muscular atrophy (SMA), a severe genetic disease ...
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Article
Amyloid-β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease
(Wiley, 2020)Reactive astrocytes and dystrophic neurites, most aberrant presynaptic elements, are found surrounding amyloid-β plaques ...
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Article
Amyloid-β reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFα from neuronal protection to death
(Nature Publishing Group, 2015)The brains of patients with Alzheimer's disease (AD) present elevated levels of tumor necrosis factor-α (TNFα), a cytokine ...