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Artículo
Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
(Elsevier, 2017)
The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative stress and inflammation were investigated in TNF-α-activated human endothelial cells. HTyr sulfate ...
Artículo
Evidence of melatonin synthesis and release by mast cells. Possible modulatory role on inflammation
(Elsevier, 2010)
Mast cells take part of armamentarium immunologic for host defense against parasitic and bacterial infections. They are derived from bone marrow progenitors and can be activated by immunological and chemical stimuli in ...
Artículo
The Immune System in Foetal Death After a Spider Bite: Case Report with Literature Review
(Omics Publishing Group, 2016-11)
Loxoscelism is caused by the bite of a spider belonging to any of the Loxosceles species. We analyse the case of a pregnant woman, 35 weeks into gestation, who was accidentally bitten by a Loxosceles rufescens, in June ...
Artículo
Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
(Wolters Kluwer Health, 2017)
Objective-Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) mediates inflammatory and potentially proatherogenic effects, whereas the role of intracellular NAMPT (iNAMPT), the rate limiting enzyme in the salvage ...
Artículo
Squalene targets pro- and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils, monocytes and macrophages
(Elsevier, 2015)
Squalene is a natural triterpene consumed as an integral part of the human diet. Increasing evidence demonstrates that squalene has antioxidant, cardioprotective and anti-carcinogenic activities. Nevertheless, its ...
Artículo
Possible involvement of the inhibition of NF-kβ factor in anti_inflammatory actions that melatonin exert on mast cells
(2016-01-08)
Melatonin is a molecule endogenously produced in a wide variety of immune cells, including mast cells (RBL-2H3). It exhibits immunomodulatory, anti-inflammatory and anti-apoptotic properties. The physiologic mechanisms ...