Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja: Envíos recientes
Mostrando ítems 221-240 de 282
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Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells
(Frontiers Media, 2017)Giant amphiphiles encompassing a hydrophilic β-cyclodextrin (βCD) component and a hydrophobic calix[4]arene (CA4) module ...
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Asymmetric organocatalytic synthesis of tertiary azomethyl alcohols: key intermediates towards azoxy compounds and α-hydroxy-β-amino esters
(Royal Society of Chemistry (Great Britain), 2017)A series of peracylated glycosamine-derived thioureas have been synthesized and their behavior as bifunctional organocatalysts ...
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Broad Scope Synthesis of Ester Precursors of Nonfunctionalized Chiral Alcohols Based on the Asymmetric Hydrogenation of α,β-Dialkyl-, α,β-Diaryl-, and α-Alkyl-β-aryl-vinyl Esters
(American Chemical Society, 2017)The catalytic asymmetric hydrogenation of trisubstituted enol esters using Rh catalysts bearing chiral phosphine-phosphite ...
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A novel potential nanophototherapeutic based on the assembly of an amphiphilic cationic ß-cyclodextrin and an anionic porphyrin
(John Wiley & Sons, 2017)The development of cyclodextrin nanoassemblies as useful carriers for photosensitizer drugs (PS) delivery in biological ...
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Biophysics and protein corona analysis of Janus cyclodextrin-DNA nanocomplexes. Efficient cellular transfection on cancer cells
(Elsevier, 2017)The self-assembling processes underlining the capabilities of facially differentiated (¿Janus¿) polycationic amphiphilic ...
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Fluorinated chaperone-ß-cyclodextrin formulations for ß-glucocerebrosidase activity enhancement in neuronopathic Gaucher disease
(American Chemical Society, 2017)Amphiphilic glycomimetics encompassing a rigid, undistortable nor-tropane skeleton based on 1,6-anhydro-L-idonojirimycin ...
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The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study
(2017)The vision of multivalency as a strategy limited to achieve affinity enhancements between a protein receptor and its ...
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Multivalent Glycosylated Nanostructures To Inhibit Ebola Virus Infection
(American Chemical Society, 2017)The infection of humans by lethal pathogens such as Ebola and other related viruses has not been properly addressed so ...
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Synthesis and reactivity studies of cationic Ir(III) alkylidines. α-hydride abstraction reactions
(Sociedad Química de México, 2017)The chemistry of late transition metal alkylidenes [M=CR2], where R is H a hydrocarbyl group, have attracted widespread ...
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Probing the Inhibitor versus Chaperone Properties of sp2-Iminosugars towards Human -Glucocerebrosidase: A Picomolar Chaperone for Gaucher Disease
(Molecular Diversity Preservation International, 2018)A series of sp2-iminosugar glycomimetics differing in the reducing or nonreducing character, the configurational pattern ...
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Experimental Measurement of Carbohydrate–Aromatic Stacking in Water by Using a Dangling-Ended DNA Model System
(Wiley-VCH, 2008)Protein–carbohydrate recognition is of fundamental importance for a large number of biological processes; carbohydrate–aromatic ...
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Docking, synthesis, and NMR studies of mannosyl trisaccharide ligands for DC-SIGN lectin
(Royal Society of Chemistry (Great Britain), 2008)DC-SIGN, a lectin, which presents at the surface of immature dendritic cells, constitutes nowadays a promising target for ...
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Synthesis and structural characterization of a binuclear iridium complex with bridging, bidentate N-heterocyclic carbene coordination of 2, 2 ':6 ', 2''-terpyridine
(Royal Society of Chemistry, 2009)Thermal activation of terpyridine in the presence of an unsaturated Ir(III) fragment stabilized by a hydrotris(pyrazolyl) borate ...
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Palladium(II) carboxylates and palladium(I) carbonyl carboxylate complexes as catalysts for olefin cyclopropanation with ethyl diazoacetate
(Royal Society of Chemistry (Great Britain), 2009)Palladium(I) carbonyl carboxylate complexes [Pd(μ-CO)(μ-RCO2)]n (R = Me, n = 4; R = CMe3, n = 6) and the corresponding ...
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Ovarian steroids regulate tachykinin and tachykinin receptor gene expression in the mouse uterus
(BioMed Central, 2009)Background: In the mouse uterus, pregnancy is accompanied by changes in tachykinin and tachykinin receptor gene expression ...
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Trinuclear copper(I) complexes with triscarbene ligands: catalysis of C–N and C–C coupling reactions
(Royal Society of Chemistry (Great Britain), 2009)Novel synthetic routes for the preparation of trinuclear copper(I) complexes with triscarbene ligands are presented, which ...
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Improved non-covalent biofunctionalization of multi-walled carbon nanotubes using carbohydrate amphiphiles with a butterfly-like polyaromatic tail
(Springer, 2010)We have developed an efficient strategy for the non-covalent functionalization of multi-walled carbon nanotubes (MWCNTs) ...
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HIV microbicides: state-of-the-art and new perspectives on the development of entry inhibitors
(Future Science, 2010)Since the discovery of HIV at the beginning of the 1980s, numerous efforts have been devoted to the search of an efficient ...
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Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition
(Nature Publishing Group, 2018)Apoptosis is a highly regulated form of programmed cell death, essential to the development and homeostasis of multicellular ...
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3-(Piperidin-1-ium-1-yl)-6-azoniaspiro[5.5]undecane dibromide monohydrate
(International Union of Crystallography, 2011)The title compound, C15H30N2 2+·2Br−·H2O, was synthesized by reaction of 4-piperidinopiperidine with dibromopentane. The ...