Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja: Envíos recientes
Mostrando ítems 1-20 de 278
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PCNA molecular recognition of different PIP motifs: Role of Tyr211 phosphorylation
(Elsevier, 2024-07)The coordination of enzymes and regulatory proteins for eukaryotic DNA replication and repair is largely achieved by ...
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A splice-altering homozygous variant in COX18 causes severe sensory-motor neuropathy with oculofacial apraxia
(Elsevier B.V., 2024-10)Cytochrome-c oxidase (COX) is part of the mitochondrial complex IV (CIV). COX deficiency is usually associated with tRNA ...
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Phosphorylation at the disordered N-end makes HuR accumulate and dimerize in the cytoplasm.
(Oxford University Press, 2024-07-05)Human antigen R (HuR) is an RNA binding protein mainly involved in maintaining the stability and controlling the translation ...
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SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
(Elsevier, 2024-03-26)The posttranslational modification of proteins critically influences many biological processes and is a key mechanism that ...
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sp2-Iminosugar Azobenzene O-glycosides: Light-sensitive Glycosidase Inhibitors with Unprecedented Tunability and Switching Factors
(Elsevier, 2024)The conventional approach to developing light-sensitive glycosidase activity regulators, involving the combination of a ...
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Speeding-up the Determination of Protein-Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR)
(American Chemical Society, 2024-01-02)STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small ...
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Atroposelective Synthesis of 2-(Quinolin-8-yl)benzyl Alcohols by Biocatalytic Dynamic Kinetic Resolutions
(Wiley, 2023-12-22)A highly enantioselective biocatalytic dynamic kinetic resolution (DKR) of 2-(quinoline-8-yl) 3-methylbenzaldehydes and ...
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Enzyme-Responsive Zr-Based Metal-Organic Frameworks for Controlled Drug Delivery: Taking Advantage of Clickable PEG-Phosphate Ligands
(American Chemical Society, 2023)We report for the first time the controlled drug release from a nanoscale Zr-based metal-organic framework (MOF), UiO-66, ...
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Continuous flow synthesis of PCN-222 (MOF-545) with controlled size and morphology: a sustainable approach for efficient production
(Royal Society of Chemistry, 2023-11-21)Zirconium-based MOFs, such as PCN-222 (MOF-545), have gained attention due to their regular porosity, tuneable pore size, ...
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On the athermal origin of flash sintering: Separating field-induced effects from Joule heating using a current ramp approach
(Pergamon-Elsevier Science LTD, 2024-03-16)Joule heating is generally acknowledged as the main driving force behind Flash Sintering. However, this view is challenged ...
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Silver-free gold-catalyzed heterocyclizations through intermolecular H-bonding activation.
(AMER Chemical Soc, 2023-01-27)Modulable monosulfonyl squaramides have been shown to exert activation of gold(I) chloride complexes through H-bonding in ...
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Dynamic Kinetic Resolution of Indole-Based Sulfenylated Heterobiaryls by Rhodium-Catalyzed Atroposelective Reductive Aldol Reaction
(Amer chemical SOC, 2023-08-30)A highly enantio- and diastereoselective dynamic kinetic resolution (DKR) of configurationally labile 3-aryl indole-2-carbaldehydes ...
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Dynamic kinetic resolution of 2-(Quinolin-8-yl)benzaldehydes: atroposelective iridium-catalyzed transfer hydrogenative allylation
(Wiley-V C H Verlag GMBH, 2023-06-30)An atroposelective Ir-catalyzed dynamic kinetic resolution (DKR) of 2-(quinolin-8- yl)benzaldehydes/1-naphthaldehydes ...
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Unveiling the Latent Reactivity of Cp* Ligands (C5Me5-) toward Carbon Nucleophiles on an Iridium Complex
(American Chemical Society, 2023)The divergent reactivity of the cationic iridium complex [(η5-C5Me5)IrCl(PMe2ArDipp2)]+ (ArDipp2 = C6H3-2,6-(C6H3-2,6-iPr2)2) ...
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Ruthenium Nanoparticles Stabilized by 1,2,3-Triazolylidene Ligands in the Hydrogen Isotope Exchange of E-H Bonds (E = B, Si, Ge, Sn) Using Deuterium Gas
(Royal Society of Chemistry, 2023)A series of ruthenium nanoparticles (Ru·MIC) stabilized with different mesoionic 1,2,3-triazolylidene (MIC) ligands were ...
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Polarized Au(i)/Rh(i) Bimetallic Pairs Cooperatively Trigger Ligand Non-innocence and Bond Activation
(Royal Society of Chemistry, 2023)The combination of molecular metallic fragments of contrasting Lewis character offers many possibilities for cooperative ...
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N-(diisopropylphosphanyl)Benzamide
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)N-(diisopropylphosphanyl)benzamide, PhC(O)NHPiPr2, has been synthesized in good yield following two alternative procedures ...
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Mechanism of Dihydrogen Splitting by An Apparent Bimetallic Frustrated Lewis Pair based on Ir(III)/Pt(0)
(Wiley-Blackwell, 2023)The incorporation of transition metals into frustrated Lewis pairs (FLPs) offers multiple opportunities for bond activation ...
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Ligand Postsynthetic Functionalization with Fluorinated Boranes and Implications in Hydrogenation Catalysis
(American Chemical Society, 2023)The incorporation of boron functionalities into transition-metal catalysts has become a promising strategy to improve ...
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Ligand and metal-centred reactivity in 2,6-bis(imino)-1,4-dihydropyridinate Zn(ii) alkyls: the dual behaviour of an intriguing type of complex
(Royal Society of Chemistry, 2023)Dihydropyridines, either free or metal-coordinated, are organic hydride transfer reductants that perform on the same ...