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Artículo
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Trehalose-polyamine/DNA nanocomplexes: impact of vector architecture on cell and organ transfection selectivity
(Royal Society of Chemistry, 2024-03-05)
A novel family of precision-engineered gene vectors with well-defined structures built on trehalose and trehalose-based macrocycles (cyclotrehalans) comprising linear or cyclic polyamine heads have been synthesized through ...
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Oleuropein and its peracetylated derivative negatively regulate osteoclastogenesis by controlling the expression of genes involved in osteoclast differentiation and function
(Royal Society of Chemistry, 2020)
During chronic inflammation, macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ligand (RANKL) have well established effects on gene networks that stimulate osteoclastogenesis, which ...
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Evolution of the catalytic mechanism at the dawn of the Baeyer-Villiger monooxygenases
(Elsevier, 2024-05-28)
Enzymes are crucial for the emergence and sustenance of life on earth. How they became catalytically active during their evolution is still an open question. Two opposite explanations are plausible: acquiring a mechanism ...
Ponencia
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Aprendizaje basado en problemas para la enseñanza de la química en la universidad
(2019)
El objetivo del trabajo es analizar la eficacia de la metodología del aprendizaje basado en problemas (ABP) en una titulación del grupo de las STEM, en concreto en tres asignaturas de 1º, 2º y 3º del Grado en Química de ...