Listar Química Orgánica por título
Mostrando ítems 285-304 de 464
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Artículo
Oleuropein and its peracetylated derivative negatively regulate osteoclastogenesis by controlling the expression of genes involved in osteoclast differentiation and function
(Royal Society of Chemistry, 2020)During chronic inflammation, macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ...
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Artículo
Olive-Oil-Derived Polyphenols Effectively Attenuate Inflammatory Responses of Human Keratinocytes by Interfering with the NF-κB Pathway
(Wiley, 2019)Primary human keratinocytes are pretreated with HTy-Ac or HTy for 30 min and stimulated with IL-1β or Toll-like receptor ...
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Artículo
Organocatalysis and Biocatalysis Hand in Hand: Combining Catalysts in One-Pot Procedures
(Wiley, 2017)Multi-step processes catalysed by several catalysts working concurrently have been developed in nature, thus improving ...
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Artículo
Osmotic stress activates nif and fix genes and induces the Rhizobium tropici CIAT 899 Nod factor production via NodD2 by up-regulation of the nodA2 operon and the nodA3 gene
(Public Library of Science, 2019)The symbiosis between rhizobia and legumes is characterized by a complex molecular dialogue in which the bacterial NodD ...
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Artículo
P450BM3-Catalyzed Oxidations Employing Dual Functional Small Molecules
(MDPI, 2019)A set of dual functional small molecules (DFSMs) containing different amino acids has been synthesized and employed ...
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Artículo
Pd(II)-Catalyzed Asymmetric Addition of Arylboronic Acids to Aliphatic N-Carbamoyl Hydrazones
(Wiley, 2022)Catalysts generated by combinations of Pd(TFA)2 and pyridine-hydrazone ligands have been applied to 1,2 addition of ...
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Artículo
Pd-Catalyzed Dynamic Kinetic Asymmetric Cross-Coupling of Heterobiaryl Bromides with N-Tosylhydrazones
(American Chemical Society, 2022)A dynamic kinetic asymmetric Pd-catalyzed cross-coupling reaction of heterobiaryl bromides with ketone N-tosylhydrazones ...
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Artículo
Pharmacological chaperone therapy for Gaucher disease: A patent review
(Taylor & Francis, 2011)Introduction: Mutations in the gene encoding for acid β-glucosidase (β-glucocerebrosidase, GlcCerase) are seen in Gaucher ...
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Artículo
Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease
(Nature Publishing Group, 2015)Gaucher disease (GD) is caused by mutations in the GBA1 gene, which encodes lysosomal β-glucocerebrosidase. Homozygosity ...
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Artículo
Pharmacological Chaperones for the Treatment of α-Mannosidosis
(American Chemical Society, 2019)α-Mannosidosis (AM) results from deficient lysosomal α-mannosidase (LAMAN) activity and subsequent substrate accumulation ...
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Tesis Doctoral
Phenolics as carbonyl scavengers: an additional protection against lipid oxidative damage in foods.
(2018-04-13)Los compuestos fenólicos, además de actuar como agentes quelantes de metales y de capturar radicales libres, también pueden ...
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Artículo
Piperidine Azasugars Bearing Lipophilic Chains: Stereoselective Synthesis and Biological Activity as Inhibitors of Glucocerebrosidase (GCase)
(American Chemical Society, 2021)We report a straightforward synthetic strategy for the preparation of trihydroxypiperidine azasugars decorated with ...
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Artículo
Plant Growth-Promoting Rhizobacteria Modulate the Concentration of Bioactive Compounds in Tomato Fruits
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)Background: The application of microorganisms as bioestimulants in order to increase the yield and/or quality of agricultural ...
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Tesis Doctoral
Plataformas multifuncionales basadas en ciclodextrinas: diseño de antitoxinas del ántrax y vectores de genes
(2010-02-12)El trabajo desarrollado en esta Tesis aprovecha precisamente la faceta como plataforma nanométrica de las CDs. En ella se ...
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Tesis Doctoral
Polihidroxialquil nitroimidazoles
(1976-03-11) -
Tesis Doctoral
Polisacáridos en aceitunas de las variedades “manzanilla” y “gordal”. Aislamiento y purificación
(1981-10-02)El objeto de este trabajo es el aislamiento y purificación de los polisacáridos que existen en las aceitunas verdes ...
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Artículo
Polycyclic Ketone Monooxygenase (PockeMO): A Robust Biocatalyst for the Synthesis of Optically Active Sulfoxides
(Multidisciplinary Digital Publishing Institute (MDPI), 2017)recently discovered, moderately thermostable Baeyer-Villiger monooxygenase, polycyclic ketone monooxygenase (PockeMO), ...
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Tesis Doctoral
Poros hidrofílicos. Crambescidina-816 un inhibidor de canales de calcio
(2010-11-26)El trabajo que se describe a continuación se reúne en cuatro capítulos. En los dos primeros se analiza el comportamiento ...
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Artículo
Positive impact of natural deep eutectic solvents on the biocatalytic performance of 5-hydroxymethyl-furfural oxidase
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)Deep eutectic solvents (DESs) have been applied as cosolvents in various biocatalytic processes during recent years. ...
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Tesis Doctoral
Preparación de conjugados alérgeno-adyuvante para el desarrollo de vacunas sintéticas
(2021-11-26)Las enfermedades alérgicas constituyen uno de los trastornos más presentes en la sociedad con una prevalencia cada vez ...