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Mostrando ítems 11-20 de 28
Artículo
Mutant prevention concentrations of fluoroquinolones for Enterobacteriaceae expressing the plasmid-carried quinolone resistance determinant qnrA1
(American Society for Microbiology, 2007-06-01)
The influence of qnrA1 on the development of quinolone resistance in Enterobacteriaceae was evaluated by using the mutant prevention concentration parameter. The expression of qnrA1 considerably increased the mutant ...
Artículo
Detection of plasmid-mediated quinolone resistance genes in clinical isolates of Enterobacter spp. in Spain
(American Society for Microbiology, 2009)
We have studied by PCR and DNA sequencing the presence of the qnrA, qnrB, qnrS, aac(6′)-Ib-cr, qepA, intI1, and ISCR1 genes in 200 clinical isolates of Enterobacter cloacae (n = 153) and E. aerogenes (n = 47) consecutively ...
Artículo
Energy-dependent accumulation of norfloxacin and porin expression in clinical isolates of Klebsiella pneumoniae and relationship to extended-spectrum β-lactamase production
(American Society for Microbiology, 2002-12-01)
The relationships between porin deficiency, active efflux of fluoroquinolones, and extended-spectrum β-lactamase (ESBL) production were determined for 53 clinical isolates of Klebsiella pneumoniae. Thirty-two ESBL-positive ...
Artículo
Identification and characterization of a new porin gene of Klebsiella pneumoniae: Its role in β-lactam antibiotic resistance
(American Society for Microbiology, 1999)
Klebsiella pneumoniae porin genes were analyzed to detect mutations accounting for the porin deficiency observed in many β-lactam-resistant strains. PCR and Southern blot analysis revealed the existence of a third porin ...
Artículo
In vivo selection of porin-deficient mutants of Klebsiella pneumoniae with increased resistance to cefoxitin and expanded-spectrum cephalosporins
(American Society for Microbiology, 1996-02-01)
Four Klebsiella pneumoniae isolates (LB1, LB2, LB3, and LB4) with increased antimicrobial resistance were obtained from the same patient. The four isolates were indistinguishable in biotype, plasmid content, lipopolysaccharide, ...
Artículo
Comparison of E-test with broth microdilution and disk diffusion for susceptibility testing of coryneform bacteria
(American Society for Microbiology, 1995)
The susceptibilities of 135 coryneform bacteria isolated from clinical samples to ampicillin (AMP), cephalothin (CR), cefoxitin (FOX), cefotaxime (CTX), erythromycin (E), ciprofioxacin (CIP), tetracycline (TE), amikacin ...
Artículo
Development of resistance during antimicrobial therapy caused by insertion sequence interruption of porin genes
(American Society for Microbiology, 1999-01-01)
We have demonstrated by using an in vitro approach that interruption of the OmpK36 porin gene by insertion sequences (ISs) is a common type of mutation that causes loss of porin expression and increased resistance to ...
Artículo
A multinational, preregistered cohort study of β-lactam/β-lactamase inhibitor combinations for treatment of bloodstream infections due to extended-spectrum-β-lactamase-producing enterobacteriaceae
(American Society for Microbiology, 2016-07-01)
The spread of extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) is leading to increased carbapenem consumption. Alternatives to carbapenems need to be investigated. We investigated whether ...
Artículo
Efficacy of cefepime and imipenem in experimental murine pneumonia caused by porin-deficient Klebsiella pneumoniae producing CMY-2 β-lactamase
(American Society for Microbiology, 2005-08-01)
Previous studies have shown decreased in vitro activity of zwitterionic cephalosporins and carbapenems against porin-deficient Klebsiella pneumoniae expressing a plasmid-mediated AmpC-type β-lactamase (PACBL). The in vitro ...
Artículo
Antimicrobial susceptibility pattern of Corynebacterium striatum
(American Society for Microbiology, 1996-11-01)
The in vitro activities of 16 antimicrobial agents against 86 strains of Corynebacterium striatum were evaluated by microdilution using cation- adjusted Mueller-Hinton broth. MICs at which 90% of strains were inhibited ...