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Artículo
Overexpression of canonical prefoldin associates with the risk of mortality and metastasis in non-small cell lung cancer
(2020-04-24)
Canonical prefoldin is a protein cochaperone composed of six di erent subunits (PFDN1 to 6). PFDN1 overexpression promotes epithelial–mesenchymal transition (EMT) and increases the growth of xenograft lung cancer (LC) ...
Artículo
Artículo
Flow Cytometry of Microencapsulated Colonies for Genetics Analysis of Filamentous Fungi
(Genetics Society of America:, 2014)
The analysis of filamentous fungi by flow cytometry has been impossible to date due to their filamentous nature and size. In this work, we have developed a method that combines single-spore microencapsulation and large-particle ...
Artículo
FACT Prevents the Accumulation of Free Histones Evicted from Transcribed Chromatin and a Subsequent Cell Cycle Delay in G1
(Public Library of Science, 2010)
The FACT complex participates in chromatin assembly and disassembly during transcription elongation. The yeast mutants affected in the SPT16 gene, which encodes one of the FACT subunits, alter the expression of G1 cyclins ...
Artículo
Chromatin reassembly factors are involved in transcriptional interference promoting HIV latency
(American Society for Microbiology, 2011)
The establishment of a stable reservoir of latently infected cells allows HIV to persist in the host. Usually, HIV infection of T cells results in integration of the viral genome, with a preference for regions in the human ...
Artículo
Genome-wide studies of mRNA synthesis and degradation in eukaryotes
(Elsevier BV, 2012)
In recent years, the use of genome-wide technologies has revolutionized the study of eukaryotic transcription producing results for thousands of genes at every step of mRNA life. The statistical analyses of the results for ...
Artículo
Artículo
Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning
(BioMed Central, 2017)
TFIIS stimulates RNA cleavage by RNA polymerase II and promotes the resolution of backtracking events. TFIIS acts in the chromatin context, but its contribution to the chromatin landscape has not yet been investigated. ...
Artículo
Asymmetric cell division requires specific mechanisms for adjusting global transcription
(Oxford University Press, 2017)
Most cells divide symmetrically into two approximately identical cells. There are many examples, however, of asymmetric cell division that can generate sibling cell size differences. Whereas physical asymmetric division ...
Artículo
Balanced production of ribosome components is required for proper G/S transition in saccharomyces cerevisiae
(American Society for Biochemistry and Molecular Biology Inc., 2013)