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Artículo
Relation between CarS expression and activation of carotenogenesis by stress in Fusarium fujikuroi
(Frontiers Media S.A., 2022)
Fusarium fujikuroi, a model organism for secondary metabolism in fungi, produces carotenoids, terpenoid pigments with antioxidant activity. Previous results indicate that carotenoid synthesis in F. fujikuroi is stimulated ...
Artículo
Prefoldin-like Bud27 influences the transcription of ribosomal components and ribosome biogenesis in Saccharomyces cerevisiae
(Cold Spring Harbor Laboratory Press, 2020)
Understanding the functional connection that occurs for the three nuclear RNA polymerases to synthesize ribosome components during the ribosome biogenesis process has been the focal point of extensive research. To preserve ...
Artículo
HmbC, a Protein of the HMG Family, Participates in the Regulation of Carotenoid Biosynthesis in Fusarium fujikuroi
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
In the fungus Fusarium fujikuroi, carotenoid production is up-regulated by light and down-regulated by the CarS RING finger protein, which modulates the mRNA levels of carotenoid pathway genes (car genes). To identify new ...
Artículo
The Total mRNA Concentration Buffering System in Yeast is Global Rather than Gene-specific
(Cold Spring Harbor Laboratory Press, 2021)
Gene expression in eukaryotes does not follow a linear process from transcription to translation and mRNA degradation. Instead it follows a circular process in which cytoplasmic mRNA decay crosstalks with nuclear transcription. ...
Artículo
Ribosomal protein eL39 is important for maturation of the nascent polypeptide exit tunnel and proper protein folding during translation
(Oxford University Press, 2022)
During translation, nascent polypeptide chains travel from the peptidyl transferase center through the nascent polypeptide exit tunnel (NPET) to emerge from 60S subunits. The NPET includes portions of five of the six ...
Artículo
The Terminal Extensions of Dbp7 Influence Growth and 60S Ribosomal Subunit Biogenesis in Saccharomyces cerevisiae
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Ribosome synthesis is a complex process that involves a large set of protein trans-acting factors, among them DEx(D/H)-box helicases. These are enzymes that carry out remodelling activities onto RNAs by hydrolysing ATP. ...
Artículo
Manganese Stress Tolerance Depends on Yap1 and Stress-Activated MAP Kinases
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Understanding which intracellular signaling pathways are activated by manganese stress is crucial to decipher how metal overload compromise cellular integrity. Here, we unveil a role for oxidative and cell wall stress ...
Artículo
Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing
(Elsevier, 2021)
Accumulation of topological stress in the form of DNA supercoiling is inherent to the advance of RNA polymerase II (Pol II) and needs to be resolved by DNA topoisomerases to sustain productive transcriptional elongation. ...
Artículo
Special Issue: Type III Secretion Systems in Human/Animal Pathogenic Bacteria
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Artículo
Enhanced Gene Regulation by Cooperation between mRNA Decay and Gene Transcription
(Elsevier, 2023)
It has become increasingly clear in the last few years that gene expression in eukaryotes is not a linear process from mRNA synthesis in the nucleus to translation and degradation in the cytoplasm, but works as a circular ...