Listar Artículos (Genética) por título
Mostrando ítems 414-433 de 455
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The ubiK protein is an accessory factor necessary for bacterial Ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ
(American Society for Biochemistry and Molecular Biology Inc., 2017)Ubiquinone (UQ), also referred to as coenzyme Q, is a widespread lipophilic molecule in both prokaryotes and eukaryotes ...
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The ubiquitin E3/E4 ligase, UBE4A, fine-tunes protein ubiquitylation and accumulation at sites of DNA damage facilitating double-strand break repair
(Elsevier, 2018)Double-strand breaks (DSBs) are critical DNA lesions that robustly activate the elaborate DNA damage response (DDR) ...
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The Ubiquitin Moiety of Ubi1 Is Required for Productive Expression of Ribosomal Protein eL40 in Saccharomyces cerevisiae
(MDPI, 2019)Ubiquitin is a highly conserved small eukaryotic protein. It is generated by proteolytic cleavage of precursor proteins ...
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The yeast and human FACT chromatin-reorganizing complexes resolve R-loop-mediated transcription-replication conflicts
(Cold Spring Harbor Laboratory Press, 2014)FACT (facilitates chromatin transcription) is a chromatin-reorganizing complex that swaps nucleosomes around the RNA ...
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The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability
(Cold Spring Harbor Laboratory Press, 1997)The yeast HPR1 gene plays an important role in genome stability, as indicated by the observation that hpr1 mutants have ...
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The yeast prefoldin-like URI-orthologue Bud27 associates with the RSC nucleosome remodeler and modulates transcription
(Oxford University Press, 2014)Bud27, the yeast orthologue of human URI/RMP, is a member of the prefoldin-like family of ATPindependent molecular ...
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Therapeutic Opportunities of Disrupting Genome Integrity inAdult Diffuse Glioma
(MDPI, 2022)Adult diffuse glioma, particularly glioblastoma (GBM), is a devastating tumor of the central nervous system. The existential ...
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Tho1, a novel hnRNP, and Sub2 provide alternative pathways for mRNP biogenesis in yeast THO mutants
(American Society for Microbiology, 2006)THO is a protein complex that functions in cotranscriptional mRNP formation. Yeast THO1 and SUB2 (Saccharomyces cerevisiae) ...
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Three Genes Involved in Different Signaling Pathways, carS, wcoA, and acyA, Participate in the Regulation of Fusarin Biosynthesis in Fusarium fujikuroi
(MDPI, 2024)The phytopathogenic fungus Fusarium fujikuroi has a rich secondary metabolism which includes the synthesis of very different ...
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Threonine overproduction in yeast strains carrying the HOM3-R2 mutant allele under the control of different inducible promoters
(American Society for Microbiology, 1999)The HOM3 gene of Saccharomyces cerevisiae codes for aspartate kinase, which plays a crucial role in ...
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Topoisomerase 1-dependent R-loop deficiency drives accelerated replication and genomic instability
(Elsevier, 2022)DNA replication is a complex process tightly regulated to ensure faithful genome duplication, and its perturbation leads ...
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Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing
(Elsevier, 2021)Accumulation of topological stress in the form of DNA supercoiling is inherent to the advance of RNA polymerase II (Pol ...
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Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability
(Elsevier, 2014)R-loops, consisting of an RNA-DNA hybrid and displaced single-stranded DNA, are physiological structures that regulate ...
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Transcription-driven DNA supercoiling counteracts H-NS-mediated gene silencing in bacterial chromatin.
(Nature Research, 2024-03-30)In all living cells, genomic DNA is compacted through interactions with dedicated proteins and/or the formation of plectonemic ...
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Transcriptional regulation by the velvet protein VE-1 during asexual development in the fungus neurospora crassa.
(American Society for Microbiology, 2022)Asexual reproduction in fungi facilitates the dispersal and colonization of new substrates and, in pathogenic fungi, allows ...
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Translocation events in the evolution of aminoacyl-tRNA synthetases
(National Academy of Sciences, 1996)We have characterized hisS, the gene encoding the histidyl-tRNA synthetase (HisRS) from the tetraodontoid fish Fugu rubripes. ...
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TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin
(eLife Sciences Publications, 2021)TRIM37 is an E3 ubiquitin ligase mutated in Mulibrey nanism, a disease with impaired organ growth and increased tumor ...
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Tubulin Folding Cofactor TBCB is a Target of the Salmonella Effector Protein SseK1
(MDPI, 2020)Salmonella enterica serovar Typhimurium is a human and animal pathogen that uses type III secretion system effectors to ...
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Type III Secretion Effectors with Arginine N-Glycosyltransferase Activity
(MDPI, 2020)Type III secretion systems are used by many Gram-negative bacterial pathogens to inject proteins, known as effectors, into ...