New therapeutic perspectives in non-alcoholic steatohepatitis

Ampuero Herrojo, Javier; Sánchez-Torrijos, Yolanda; Aguilera, Virginia; Bellido, Francisco; Romero Gómez, Manuel

doi:10.1016/j.gastrohep.2017.07.006

Artículo

dc.creator	Ampuero Herrojo, Javier	es
dc.creator	Sánchez-Torrijos, Yolanda	es
dc.creator	Aguilera, Virginia	es
dc.creator	Bellido, Francisco	es
dc.creator	Romero Gómez, Manuel	es
dc.date.accessioned	2021-05-05T16:05:59Z
dc.date.available	2021-05-05T16:05:59Z
dc.date.issued	2018-02-23
dc.identifier.citation	Ampuero Herrojo, J., Sánchez-Torrijos, Y., Aguilera, V., Bellido, F. y Romero Gómez, M. (2018). New therapeutic perspectives in non-alcoholic steatohepatitis. Revista Española De Enfermedades Digestivas, 41 (2), 128-142.
dc.identifier.issn	1130-0108	es
dc.identifier.uri	https://hdl.handle.net/11441/108571
dc.description.abstract	Management of non-alcoholic steatohepatitis is focused on restitution of metabolic derangement, weight loss and drugs able to improve steatosis, ballooning and fibrosis. Life-style interventions based on Mediterranean diet and increasing physical activity are the first line ther apy. In patients with unsuccessful life-style intervention several drugs are under development: agonist PPAR, agonist GLP-1R and agonist FXR together with drugs focussing on inflammation, ballooning, apoptosis and fibrosis. Bariatric surgery or advanced endoscopy are reserved for morbid obese without response to life-style intervention and weighting loss drugs.	es
dc.format	application/pdf	es
dc.format.extent	15 p.	es
dc.language.iso	eng	es
dc.publisher	Elsevier	es
dc.relation.ispartof	Revista Española De Enfermedades Digestivas, 41 (2), 128-142.
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject	Body mass index	es
dc.subject	Visceral obesity	es
dc.subject	Obeticolic acid	es
dc.subject	Peroxisome proliferator-activated receptor	es
dc.subject	Glucagon-like peptide-1 receptor agonists	es
dc.subject	Índice de masa corporal	es
dc.subject	Obesidad visceral	es
dc.subject	Ácido obeticólico	es
dc.subject	Peroxisome proliferator activated receptor	es
dc.subject	Agonistas glucagon-like peptide-1 receptor	es
dc.title	New therapeutic perspectives in non-alcoholic steatohepatitis	es
dc.type	info:eu-repo/semantics/article	es
dcterms.identifier	https://ror.org/03yxnpp24
dc.type.version	info:eu-repo/semantics/publishedVersion	es
dc.rights.accessRights	info:eu-repo/semantics/openAccess	es
dc.contributor.affiliation	Universidad de Sevilla. Departamento de Medicina	es
dc.identifier.doi	10.1016/j.gastrohep.2017.07.006	es
dc.journaltitle	Revista Española De Enfermedades Digestivas	es
dc.publication.volumen	41	es
dc.publication.issue	2	es
dc.publication.initialPage	128	es
dc.publication.endPage	142	es

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