Hypoxic hepatitis as diabetic ketoacidosis complication

Abstract

Hypoxic hepatitis (HH) (also known as ischemic hepatitis or shock liver) is characterized by a dramatic but transient rise in serum concentrations of hepatic enzymes caused by anox ic necrosis of centrilobular liver cells (1). Although the patho genesis is multifactorial –cardiac failure, respiratory failure and toxic-septic shock– (2), the final common pathway is the hepatocellular dysfunction secondary to low levels of oxygen for metabolic processes.