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Mostrando ítems 11-18 de 18
Artículo
Dual Independent Roles of the p24 Complex in Selectivity of Secretory Cargo Export from the Endoplasmic Reticulum
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
The cellular mechanisms that ensure the selectivity and fidelity of secretory cargo protein transport from the endoplasmic reticulum (ER) to the Golgi are still not well understood. The p24 protein complex acts as a specific ...
Artículo
Osh proteins regulate COPII-mediated vesicular transport of ceramide from the endoplasmic reticulum in budding yeast
(Company of Biologists Ltd, 2014)
Lipids synthesized at the endoplasmic reticulum (ER) are delivered to the Golgi by vesicular and non-vesicular pathways. ER-to-Golgi transport is crucial for maintaining the different membrane lipid composition and identities ...
Artículo
GPI anchors: Regulated as needed
(Rockefeller University Press, 2023)
GPI anchoring is an essential post-translational modification in eukaryotes that links proteins to the plasma membrane. In this issue, Liu et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202208159) suggest, for the ...
Artículo
Limited ER quality control for GPI-anchored proteins
(Rockefeller University Press, 2016)
Endoplasmic reticulum (ER) quality control mechanisms target terminally misfolded proteins for ER-associated degradation (ERAD). Misfolded glycophosphatidylinositol-anchored proteins (GPI-APs) are, however, generally poor ...
Capítulo de Libro
Aplicación de un Ciclo de Mejora en la asignatura de Fundamentos de la vida del Grado en Educación Primaria
(Universidad de Sevilla, 2022)
En los tiempos actuales necesitamos de ciudadanos capaces de lidiar con la incertidumbre. En un ambiente tecnológico y social en continuo cambio nuestros estudiantes necesitan poseer una actitud proactiva ante el aprendizaje ...
Tesis Doctoral
Análisis funcional del complejo p24 en Saccharomyces cerevisiae
(2010)
El propósito general de esta tesis es el análisis molecular de la función del complejo p24 en los procesos selectivos de transporte vesicular entre el RE y el aparato de Golgi en la levadura Saccharomyces cerevisiae. ... ...
Artículo
Impact of Sphingolipids on Protein Membrane Trafficking
(Elsevier, 2023)
Membrane trafficking is essential to maintain the spatiotemporal control of protein and lipid distribution within membrane systems of eukaryotic cells. To achieve their functional destination proteins are sorted and ...
Artículo
Quality-controlled ceramide-based GPI-anchored protein sorting into selective ER exit sites
(Elsevier, 2022)
Glycosylphosphatidylinositol-anchored proteins (GPI-APs) exit the endoplasmic reticulum (ER) through a specialized export pathway in the yeast Saccharomyces cerevisiae. We have recently shown that a very-long acyl chain ...