dc.creator | Moreno Fernández, Ana María | es |
dc.creator | Macías García, Laura | es |
dc.creator | Valverde Moreno, R. | es |
dc.creator | Ortiz, T. | es |
dc.creator | Fernández Rodríguez, Ana | es |
dc.creator | Moliní Estrada, A. | es |
dc.creator | De-Miguel, Manuel | es |
dc.date.accessioned | 2021-04-26T16:04:17Z | |
dc.date.available | 2021-04-26T16:04:17Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Moreno Fernández, A.M., Macías García, L., Valverde Moreno, R., Ortiz, T., Fernández Rodríguez, A., Moliní Estrada, A. y De-Miguel, M. (2019). Autohemotherapy with ozone as a possible effective treatment for Fibromyalgia. Acta Reumatologica Portuguesa, 44 (3), 244-249. | |
dc.identifier.issn | 0303-464X | es |
dc.identifier.uri | https://hdl.handle.net/11441/107851 | |
dc.description.abstract | Objective: The objective of thisstudy isto evaluate the
effectiveness of autohemotherapy with ozone in the
management of fibromyalgia (FM).
Design: 20 FM patients(according to the criteria of the
American College of Rheumatology), were treated with
10 sessions of ozone hemotherapy (2 sessions per
week) with a concentration of 30-60 mcgr/ml. The
health condition of the patients was evaluated before
and after treatment, through the Fibromyalgia Impact
Questionnaire (FIQ). Blood samples were obtained
from all patients by venous puncture for biochemical
routine analysis and serotonin levels in serum and the
following peripheral blood mononuclear cells (BMCs)
were isolated for oxidative stress quantification:reactive
oxygen species (ROS) generation, and lipid peroxidation (LP) and protein carbonyl (PC) content, as these
are signs of oxidative cell damage.
Results: All patients treated with ozone reported an
improvement in sleep and mental alertness, a marked
decrease of asthenia accompanied by a decrease of FIQ
as well as tender points, and a moderate increase of
serotonin levels. Also, an important decrease of LP and
PC was observed; ROS also decreased, although less
obvious, which indicates a reduction in oxidative stress
levels.
Conclusions: The autohemotherapy with ozone in patients with FM showed an important decline of tender
points and FIQ score, as well as a decrease of oxidative
stress levels. This treatment allows patients to face life
with greater vitality and less drug use, diminishing harmful side effects. Further investigation should be
carried out, including groups with more patients and
clinical trials, to elucidate the effect of ozone therapy in
patients suffering from FM. | es |
dc.format | application/pdf | es |
dc.format.extent | 6 p. | es |
dc.language.iso | eng | es |
dc.relation.ispartof | Acta Reumatologica Portuguesa, 44 (3), 244-249. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Fibromyalgia | es |
dc.subject | Ozone | es |
dc.subject | Hemotherapy | es |
dc.subject | Serotonin | es |
dc.subject | Oxidative stress | es |
dc.title | Autohemotherapy with ozone as a possible effective treatment for Fibromyalgia | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Citología e Histología Normal y Patológica | es |
dc.journaltitle | Acta Reumatologica Portuguesa | es |
dc.publication.volumen | 44 | es |
dc.publication.issue | 3 | es |
dc.publication.initialPage | 244 | es |
dc.publication.endPage | 249 | es |