Article
Obstetric outcomes of sars-cov-2 infection in asymptomatic pregnant women
Author/s | Cruz Lemini, Monica
Ferriols Perez, Elena Cruz Conty, Maria Luisa Cano Aguilar, Africa Encinas Pardilla, Maria Begoña Prats Rodríguez, Pilar Ostos, Rosa Catalina Coello, Monica Sáinz Bueno, José Antonio |
Department | Universidad de Sevilla. Departamento de Cirugía |
Publication Date | 2021-01-15 |
Deposit Date | 2021-02-16 |
Published in |
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Abstract | Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if ... Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13–3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms. |
Project ID. | COV20 / 00021
JR19 / 00047 |
Citation | Cruz Lemini, M., Ferriols Perez, E., de la Cruz Conty, M.L., Cano Aguilar, A., Encinas Pardilla, M.B., Prats Rodríguez, P.,...,Sáinz Bueno, J.A. (2021). Obstetric outcomes of sars-cov-2 infection in asymptomatic pregnant women. Viruses, 13 (1), 1-12. |
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