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dc.creatorCruz Lemini, Monicaes
dc.creatorFerriols Perez, Elenaes
dc.creatorCruz Conty, Maria Luisaes
dc.creatorCano Aguilar, Africaes
dc.creatorEncinas Pardilla, Maria Begoñaes
dc.creatorPrats Rodríguez, Pilares
dc.creatorOstos, Rosaes
dc.creatorCatalina Coello, Monicaes
dc.creatorSáinz Bueno, José Antonioes
dc.date.accessioned2021-02-16T12:20:37Z
dc.date.available2021-02-16T12:20:37Z
dc.date.issued2021-01-15
dc.identifier.citationCruz Lemini, M., Ferriols Perez, E., de la Cruz Conty, M.L., Cano Aguilar, A., Encinas Pardilla, M.B., Prats Rodríguez, P.,...,Sáinz Bueno, J.A. (2021). Obstetric outcomes of sars-cov-2 infection in asymptomatic pregnant women. Viruses, 13 (1), 1-12.
dc.identifier.issn1999-4915es
dc.identifier.urihttps://hdl.handle.net/11441/105030
dc.description.abstractAround two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13–3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms.es
dc.description.sponsorshipInstituto de Salud Carlos III — Ministerio de Sanidad de España Beca COV20 / 00021es
dc.formatapplication/pdfes
dc.format.extent12es
dc.language.isoenges
dc.publisherMDPIes
dc.relation.ispartofViruses, 13 (1), 1-12.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectSARS-CoV-2es
dc.subjectPregnancyes
dc.subjectCoronaviruses
dc.subjectAsymptomatic infectiones
dc.subjectPerinatal outcomeses
dc.subjectDeliveryes
dc.subjectMaternal complicationses
dc.titleObstetric outcomes of sars-cov-2 infection in asymptomatic pregnant womenes
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Cirugíaes
dc.relation.projectIDCOV20 / 00021es
dc.relation.projectIDJR19 / 00047es
dc.relation.publisherversionhttps://doi.org/10.3390/v13010112es
dc.identifier.doidoi.org/10.3390/v13010112es
dc.journaltitleViruseses
dc.publication.volumen13es
dc.publication.issue1es
dc.publication.initialPage1es
dc.publication.endPage12es

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