Artículo
Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata
Autor/es | Barreales Suárez, Sofía
Callejón Mochón, Manuel Azoulay, Stéphane Bello López, Miguel Ángel Fernández Torres, Rut |
Departamento | Universidad de Sevilla. Departamento de Química Analítica |
Fecha de publicación | 2018 |
Fecha de depósito | 2024-01-11 |
Publicado en |
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Resumen | A procedure based on microwave assisted extraction for the determination of 6 pharmaceuticals in samples of Lavandula dentata, Salicornia ramosissima and Juncus sp. by liquid chromatography-quadrupole time of flight mass ... A procedure based on microwave assisted extraction for the determination of 6 pharmaceuticals in samples of Lavandula dentata, Salicornia ramosissima and Juncus sp. by liquid chromatography-quadrupole time of flight mass spectrometry (LC-QTOF/MS) was optimized and validated. Best results were obtained using microwave assisted extraction of 1.0 g of homogeneous lyophilized samples and 5 mL of a mixture ACN:H2O (1:1 v/v) as extracting solvent. Analytical recoveries ranged from 60 to 107% with relative standard deviation (RSD) lower than 15%. Limits of quantitation (LOQ) for the 6 pharmaceuticals flumequine (FLM), carbamazepine (CBZ), ciprofloxacin (CPR), enrofloxacin (ENR), diclofenac (DCL), and ibuprofen (IBU) were in the range 20.8–125 ng g− 1. The method was satisfactory applied for an uptake study in Lavandula dentata samples finding quantifying concentrations of FLM and CBZ in roots, leaf and stem. |
Agencias financiadoras | Ministerio de Educación, Cultura y Deporte (MECD). España European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER) |
Identificador del proyecto | CTM2015-67902-C-1-P
UNSE10-1E-429 |
Cita | Barreales Suárez, S., Callejón Mochón, M., Azoulay, S., Bello López, M.Á. y Fernández Torres, R. (2018). Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry Determination of Six Pharmaceuticals in Vegetal Biota. Uptake Study in Lavandula Dentata. Science of the Total Environment, 622-623, 655-663. https://doi.org/10.1016/j.scitotenv.2017.11.244. |
Ficheros | Tamaño | Formato | Ver | Descripción |
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LIQUID CHROMATOGRAPHY.pdf | 892.3Kb | [PDF] | Ver/ | |