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      Human Mesenchymal Stem Cells Prevent Neurological Complications of Radiotherapy 

      Soria Escoms, Bernat; Martín Montalvo, Alejandro; Aguilera García, Yolanda; Mellado, Nuria; López Beas, Javier; Herrera-Herrera, Isabel; López, Escarlata; Barcia, Juan A.; Álvarez Dolado, Manuel; Hmadcha, Abdelkrim; Capilla González, Vivian (Frontiers Media S.A., 2019-05-16)
      Radiotherapy is a highly effective tool for the treatment of brain cancer. However, radiation also causes detrimental ...
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      LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus 

      Cobo Vuilleumier, Nadia; Lorenzo, Petra I.; García Rodríguez, Noelia; Herrera Gómez, Irene G.; Fuente Martín, Esther; López Noriega, Livia; Mellado Gil, José Manuel; Romero Zerbo, Silvana Y.; Lachaud, Christian; Hmadcha, Abdelkrim; Sánchez Palazón, Luis; Martín Montalvo, Alejandro; Soria Escoms, Bernat; Gauthier, Benoit R. (Nature Publishing Group, 2018-04-16)
      Type 1 diabetes mellitus (T1DM) is due to the selective destruction of islet beta cells by immune cells. Current therapies ...
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      Metabolic Reprogramming by Acly Inhibition Using SB-204990 Alters Glucoregulation and Modulates Molecular Mechanisms Associated with Aging 

      Sola García, Alejandro; Cáliz Molina, María Ángeles; Espadas, Isabel; Petr, Michael; Panadero Morón, Concepción; González Morán, Daniel; Martín Vázquez, María Eugenia; Narbona Pérez, Álvaro Jesús; López Noriega, Livia; Martínez Corrales, Guillermo; Martín Montalvo, Alejandro (Springer Nature, 2023)
      ATP-citrate lyase is a central integrator of cellular metabolism in the interface of protein, carbohydrate, and lipid ...
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      Metformin-mediated increase in DICER1 regulates microRNA expression and cellular senescence 

      Noren Hooten, Nicole; Martín Montalvo, Alejandro; Dluzen, Douglas F.; Zhang, Yongqing; Bernier, Michel; Zonderman, Alan B.; Becker, Kevin G.; Gorospe, Myriam; Cabo, Rafael de (Anatomical Society of Great Britain and Ireland, John Wiley & Sons, 2016)
      Metformin, an oral hypoglycemic agent, has been used for decades to treat type 2 diabetes mellitus. Recent studies ...
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      Molecular modelling of islet β-cell adaptation to inflammation in pregnancy and gestational diabetes mellitus 

      Lorenzo, Petra I.; Martín Montalvo, Alejandro; Cobo Vuilleumier, Nadia; Gauthier, Benoit R. (Multidisciplinary Digital Publishing Institute (MDPI), 2019)
      Gestational diabetes mellitus (GDM), a metabolic disease that develops with the increase in insulin resistance during late ...
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      PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus 

      Mellado Gil, José Manuel; Jiménez Moreno, Carmen María; Martín Montalvo, Alejandro; Álvarez Mercado, Anabel; Fuente Martín, Esther; Cobo Vuilleumier, Nadia; Lorenzo, Petra I.; Gracia Herrera Gómez, Irene de; López Noriega, Livia; Quesada, Iván; Gauthier, Benoit R. (Springer Nature, 2016)
      [Aims/hypothesis]: A strategy to enhance pancreatic islet functional beta cell mass (BCM) while restraining inflammation, ...
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      The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity article 

      Mellado Gil, José Manuel; Fuente Martín, Esther; Lorenzo Ovejero, Petra Isabel; Cobo Vuilleumier, Nadia; López Noriega, Livia; Martín Montalvo, Alejandro; Gracia Herrera Gómez, Irene de; Ceballos Chávez, María; Romero Zerbo, Silvana Y.; Hmadcha, Abdelkrim; Soria Escoms, Bernat; Bermúdez Silva, Francisco Javier; Reyes, José C.; Gauthier, Benoit R. (Springer Nature [academic journals on nature.com, 2018)
      HMG20A (also known as iBRAF) is a chromatin factor involved in neuronal differentiation and maturation. Recently small ...
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      Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy 

      Hmadcha, Abdelkrim; Martín Montalvo, Alejandro; Gauthier, Benoit R.; Soria Escoms, Bernat; Capilla González, Vivian (Frontiers Media S.A., 2020)
      Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of ...