Author profile: Bachiller, Sara
Institutional data
Name | Bachiller, Sara |
Department | Bioquímica Médica y Biología Molecular e Inmunología |
Knowledge area | Bioquímica y Biología Molecular |
Professional category | Investigadora Contratada (Ramón y Cajal) |
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Statistics
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No. publications
12
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No. visits
1061
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No. downloads
1100
Publications |
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Article
LPS priming before plaque deposition impedes microglial activation and restrains Abeta pathology in the 5xFAD mouse model of Alzheimer's disease.
(Elsevier, 2023)
Microglia have an innate immunity memory (IIM) with divergent functions in different animal models of neurodegenerative ... |
Article
A metagenome-wide association study of HIV disease progression in HIV controllers
(Elsevier, 2023)
Some HIV controllers experience immunologic progression with CD4+ T cell decline. We aimed to identify genetic factors ... |
Article
Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease
(2023)
Background Alzheimer’s disease (AD) is a progressive multifaceted neurodegenerative disorder for which no disease-modifying ... |
Article
Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner
(BMC, 2022)
Background The risk of developing Alzheimer’s disease (AD) is modulated by genetic and environmental factors. Early-life ... |
Article
Immune defects associated with lower SARS-CoV-2 BNT162b2 mRNA vaccine response in aged people
(Journal of clinical investigation, 2022)
The immune factors associated with impaired SARS-CoV-2 vaccine response in elderly people are mostly unknown. We studied ... |
Article
Acute systemic LPS-exposure impairs perivascular CSF distribution in mice
(Biomed Central LTD, 2021)
The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital for waste clearance in the brain. The ... |
Article
The Other Side of SARS-CoV-2 Infection: Neurological Sequelae in Patients
(Frontiers Media S.A., 2021)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread around the globe causing coronavirus disease ... |
Article
The effect of electroconvulsive therapy on neuroinflammation, behavior and amyloid plaques in the 5xFAD mouse model of Alzheimer's disease
(Nature Publishing Group, 2021)
Microglial cells are affected in Alzheimer’s disease (AD) and interact with amyloid-beta (Aβ) plaques. Apart from memory ... |
Article
The HERC proteins and the nervous system
(Elsevier, 2021)
The HERC protein family is one of three subfamilies of Homologous to E6AP C-terminus (HECT) E3 ubiquitin ligases. Six HERC ... |
Article
The Ubiquitin Proteasome System in Neuromuscular Disorders: Moving Beyond Movement
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
Neuromuscular disorders (NMDs) affect 1 in 3000 people worldwide. There are more than 150 different types of NMDs, where ... |
Article
HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System
(Springer, 2018)
A missense mutation in HERC1 provokes loss of cerebellar Purkinje cells, tremor, and unstable gait in tambaleante (tbl) ... |
Article
HERC 1 Ubiquitin Ligase Mutation Affects Neocortical, CA3 Hippocampal and Spinal Cord Projection Neurons: An Ultrastructural Study
(Frontiers Media, 2016)
The spontaneous mutation tambaleante is caused by the Gly483Glu substitution in the highly conserved N terminal RCC1-like ... |